Results 51 to 60 of about 705,383 (355)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Design of Low-Power Structural FIR Filter Using Data-Driven Clock Gating and Multibit Flip-Flops
Journal of Electrical and Computer Engineering, 2020 Optimization for power is one of the most important design objectives in modern digital signal processing (DSP) applications. The digital finite duration impulse response (FIR) filter is considered to be one of the most essential components of DSP, and ...
Lamjed Touil +3 more
doaj +1 more source
On the eigenfilter design method and its applications: a tutorial [PDF]
, 2003 The eigenfilter method for digital filter design involves the computation of filter coefficients as the eigenvector of an appropriate Hermitian matrix.
Nguyen, Truong Q. +2 more
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Harmonic scheduling of linear recurrences in digital filter design [PDF]
, 1992 Linear difference equations involving recurrences are fundamental equations that describe many important signal processing applications. For many high sample rate digital filter applications, we need to effectively parallelize the linear difference ...
Dutt, Nikil +2 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Design of multi-decimation rate digital filter for sigma-delta ADC
Dianzi Jishu Yingyong, 2022 Based on the standard 0.18 μm process, a digital decimation filter applied to the Sigma-Delta analog-to-digital converter is designed, which can change the decimation rate and adapt to different signal bandwidths. The filter adopts multi-stage decimation
Wang Yao, Bu Gang
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
The Design Of Intelligent Filter For EEG
MATEC Web of Conferences, 2018 EEG data processing method is usually digital filter designed by the traditional method. Its disadvantage is the transition zone is wide and the filtering effect is poor.
Yue Dachao, Liu Haikuan
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source