Results 41 to 50 of about 5,255,523 (302)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Evaluation of autonomic nervous system activity in intradialytic hypotension using entropy and skin sympathetic nerve activity

Frontiers in Neuroscience, 2023
IntroductionThe function of the autonomic nervous system (ANS) is crucial in the development of intradialytic hypotension (IDH). This study introduced the entropy of heart rate variability (HRV) and skin sympathetic nerve activity (SKNA) to provide a ...
Jiayi Li, Yantao Xing, Yike Zhang, Chang Cui, Jing Wang, Jianqing Li, Chengyu Liu   +6 more
doaj   +1 more source

The First Digital Losers [PDF]

, 2019
AbstractAs we have seen, censorship is a real and serious problem when it comes to the tech giants. However, when they use the word “censorship” themselves, they often have something completely different in mind. That other something is copyright.
Frederik Stjernfelt, Anne Mette Lauritzen   +1 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Radiomic Feature-Based Predictive Model for Microvascular Invasion in Patients With Hepatocellular Carcinoma

Frontiers in Oncology, 2020
ObjectiveThis study aimed to build and evaluate a radiomics feature-based model for the preoperative prediction of microvascular invasion (MVI) in patients with hepatocellular carcinoma.MethodsA total of 145 patients were retrospectively included in the ...
Mu He, Peng Zhang, Xiao Ma, Baochun He, Chihua Fang, Fucang Jia   +5 more
doaj   +1 more source

From the Editor [PDF]

, 2014
[Excerpt] Welcome to Issue no. 2 of Practical Technology for Archives. As with our first issue this issue has a digital focus. It is understandable that this should be the case since many archivists work extensively with digital tools and increasingly ...
Miles, Randall
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Magnesium degradation-induced variable fixation plates promote bone healing in rabbits

Journal of Orthopaedics and Traumatology
Background Both initial mechanical stability and subsequent axial interfragmentary micromotion at fracture ends play crucial roles in fracture healing.
Jian Wen, Yu Zeng, Shenghui Su, Meiling Song, Zhe Wang, Xiaofan Chen, Xieping Dong   +6 more
doaj   +1 more source

Analysis of an improved fractional-order model of boundary formation in the Drosophila large intestine dependent on Delta-Notch pathway

Advances in Difference Equations, 2020
In this paper, an improved fractional-order model of boundary formation in the Drosophila large intestine dependent on Delta-Notch pathway is proposed for the first time. The uniqueness, nonnegativity, and boundedness of solutions are studied.
Deshun Sun, Lingyun Lu, Fei Liu, Li Duan, Daping Wang, Jianyi Xiong   +5 more
doaj   +1 more source