FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Business process digitalization and efficiency of corporate working capital management
International Review of Economics & FinanceThe turbulence in the global economy and trade environment has increased uncertainty for firms, making effective working capital management (WCM) crucial for navigating these challenges.
Disheng Wang, Han Nie
doaj +1 more source
Smartness. The face of the integration in the new “performing” society [PDF]
, 2018 Economia, potere, così come case, persone e lavoro, ma prima di ogni altra cosa città: tutto negli ultimi anni è chiamato a diventare “smart”. È questa l’era della smart economy, della smart governance, della smart home, delle smart people, dello smart
Iannone, Roberta
core
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Proxy of democracy? : metaphors of connection as arguments against representation [PDF]
, 2012 This paper aims to assess the arguments that claim representative democracy may be enhanced or replaced by an updated electronic version. Focusing on the dimension of elections and electioneering as the core mechanism of representative democracy I will ...
Cuono, Massimo
core
E-democracy: exploring the current stage of e-government [PDF]
, 2014 Governments around the world have been pressured to implement e-Government programs in order to improve the government-citizen dialogue. The authors of this article review prior literature on such efforts to find if they lead to increased democratic ...
Gelders, Dave +2 more
core +3 more sources
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
An Analysis of Hotspots, Subject Structure, and Emerging Trends in Digital Governance Research
SAGE OpenThe widespread adoption of digital technology have catalyzed a surge in digital governance (DG). This paper aims to conduct a systematic analysis of 4,782 documents retrieved from the WOS database.
Chuanfeng Sun +2 more
doaj +1 more source
PECULIARITIES OF THE DIGITALIZATION PROCESS OF PUBLIC GOVERNANCE IN DEVELOPED COUNTRIES [PDF]
, 2021 М. Ю. Павлов
openalex +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source