Results 51 to 60 of about 590,418 (344)

Australian local governments and the early national broadband network roll-out: an online survey [PDF]

, 2016
A recent decision by the Australian Federal Government to reassess the scale of the National Broadband Network (NBN) will leave the country with a patchwork of different levels of access to the infrastructure. This intensifies the need to investigate and
Alizadeh, Tooran, Shearer, Heather
core   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Identification and prediction of the degree of multidimensional returning to poverty risk for the household in China through the novel hybrid model: Based on the survey data of China Family Panel Studies (CFPS)

Heliyon
In China, absolute poverty has been effectively eliminated, but this does not signify the complete eradication of poverty. Instead, poverty persists in the forms of relative and secondary poverty.
Jinsong Zhang, Tonggen Ding, Linmao Ma
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Prediction of the effect of bike-sharing on urban carbon emission reduction: Evidence from Beijing

Journal of Urban Management
Bike-sharing is regarded as a green and economical public transport mode. However, how to scientifically predict its carbon emission reduction effect is still on the way. This article builds an assessment model for emission reduction of bike-sharing. The
Hui Zhao, Zhong Wang, Jiaming Luo, Fangru Hu   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Spatiotemporal patterns and drivers of coupling coordination between digital technological innovation and economic resilience in the Yangtze river economic belt

Scientific Reports
The synergistic evolution of digital technological innovation (DTI) and urban economic resilience (UER) has become an inherent requirement for the high-quality development of urban agglomerations.
Libin Guo, Kang Liu
doaj   +1 more source

Research on digital governance based on Web of Science—a bibliometric analysis

Frontiers in Political Science
Exploring digital governance is essential for grasping how technology can be employed to enhance public services, boost efficiency, and foster transparency and engagement.
Zhao Lin, Mohd Rizal Yaakop
doaj   +1 more source

Topological genealogy: a methodology to research transnational digital governance in/through/as change [PDF]

, 2021
Mathias Decuypere, Steven Lewis
openalex   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source