Results 51 to 60 of about 49,458,790 (301)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Digital Health & Care Innovation Centre Phase 2 – Year 3 Annual Report (August 2021 to July 2022) [PDF]
, 2022 This Year 3 annual report sets out the significant impact made by DHI over the past 12 months with continued success to report evident, including 5 projects transferred to other organisations as ready to scale.
Digital Health & Care Institute (DHI)
core +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Akofena: Within the framework of the Algerian vision that emphasizes the importance of digital transformation in all sectors, including the health sector, the Algerian Ministry of Health intends to develop an integrated digital health system, through the ...
Analytical Sight on the Algerian Digital Health Strategy 2023-2027
doaj +1 more source
Asian Medical Journal and Alternative Medicine, 2021 -
Somchai Bovornkitti +1 more
openaire +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
2023 Canadian Digital Health Survey
The Canadian Digital Health Survey is a series of surveys conducted annually commissioned by Canada Health Infoway (Infoway) through a third-party vendor.
Canada Health Infoway
core +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Social media language of healthcare super-utilizers
npj Digital Medicine, 2021 An understanding of healthcare super-utilizers’ online behaviors could better identify experiences to inform interventions. In this retrospective case-control study, we analyzed patients’ social media posts to better understand their day-to-day behaviors
Sharath Chandra Guntuku +5 more
doaj +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source