Results 71 to 80 of about 3,182,213 (272)

Online outsiders within\ud [PDF]

, 2010
Heightened attention to technological diffusion and informational inequalities is of\ud particular societal concern, given the increasing mediation of everyday life whereby\ud web-based initiatives abound and an increasing amount of information on ...
Cheong, Pauline Hope, Martin, Judith
core  

Digital libraries for the developing world [PDF]

, 2006
Digital libraries (DLs) are the killer app for information technology in developing countries. Priorities here include health, agriculture, nutrition, hygiene, sanitation, and safe drinking water. Computers are not a priority, but simple, reliable access
Witten, Ian H.
core   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Race representation matters in cancer care

The Lancet: Digital Health, 2021
The Lancet Digital Health
doaj   +1 more source

Jefferson Digital Commons quarterly report: October-December 2019 [PDF]

, 2019
This quarterly report includes: Articles Dean\u27s Research Development Lunch Conference Dissertations Educational Materials From the Archives Grand Rounds and Lectures Journals and Newsletters Population Health Presentation Materials Posters Reports ...
Copeland, LIBT, James, Duinkerken, MSI, Kelsey, Gordon, MSLIS, MEd, MA, Larissa   +2 more
core   +2 more sources

The ethics of digital well-being: a multidisciplinary perspective [PDF]

This chapter serves as an introduction to the edited collection of the same name, which includes chapters that explore digital well-being from a range of disciplinary perspectives, including philosophy, psychology, economics, health care, and education ...
A Abukonna, A Alexandrova, A Elder, A Ferretti, A Jobin, A Orben, A Orben, AM Wood, B Fröding, B Goldacre, B Mittelstadt, C Burr, C Burr, C Woodard, CD Ryff, CJ Ferguson, D Hausman, D Howard, D Jeske, D Kahneman, D Lupton, D Parfit, DA Ellis, DB Dwyer, DM Haybron, DM Haybron, E Brynjolfsson, E Diener, E Lin, E Palm, ED Diener, F Greaves, FA Huppert, G Fletcher, I Robeyns, J Garde-Hansen, J Pugh, J Torous, J Williams, JN Craig, JW Galbraith, K Binmore, K Layous, K Sterelny, L Floridi, L Floridi, L Floridi, LK Ma, LW Sumner, M Bishop, M Burke, M Csikszentmihalyi, M Nussbaum, M Themistocleous, MC Nussbaum, MEP Seligman, MR Munafò, MR Munafò, N Kosmyna, NC Manson, NH Frijda, NS Kim, P Henson, P Stokes, P Verduyn, R Challen, R Crisp, R Sharp, R Yost-Dubrow, RA Calvo, RA Calvo, RJ Watson, RM Ryan, RM Ryan, RR Faden, S Allen, S Ghafur, S Leigh, S Sterckx, S Vallor, S Vallor, T Burns, T Hills, T Justinia, TK Mackey, TL Beauchamp, V Tiberius   +86 more
core   +1 more source

Public health strategies to reduce sugar intake in the UK: An exploration of public perceptions using digital spaces [PDF]

, 2018
Objective: To explore UK public perceptions of children's sugar consumption, Public Health England's Change4Life Sugar Smart app and the Soft Drinks Industry Levy, using solicited and unsolicited digital data.
Afshin, Arden, Boles, Bostrom, Cabrera-Escobar, Cho, Draper, Fade, Giles, Hill, Hsieh, Julia, Kozinets, Murphy, Polivy, Roberts, SACN (Scientific Advisory Committee on Nutrition), Sinnenberg, Thow, Watson, WHO (World Health Organization), Wrieden   +21 more
core   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source