Results 91 to 100 of about 10,789,874 (387)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Human Mobility Monitoring in Very Low Resolution Visual Sensor Network
Sensors, 2014 This paper proposes an automated system for monitoring mobility patterns using a network of very low resolution visual sensors (30 × 30 pixels). The use of very low resolution sensors reduces privacy concern, cost, computation requirement and power ...
Nyan Bo Bo +13 more
doaj +1 more source
An image copyright authentication model based on blockchain and digital watermarking [PDF]
, 2023 Huang Xiaosheng, Wu Yi
openalex +1 more source
Deep learning for digital pathology image analysis: A comprehensive tutorial with selected use cases
Journal of Pathology Informatics, 2016 Background: Deep learning (DL) is a representation learning approach ideally suited for image analysis challenges in digital pathology (DP). The variety of image analysis tasks in the context of DP includes detection and counting (e.g., mitotic events ...
A. Janowczyk, A. Madabhushi
semanticscholar +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Digital mammography, cancer screening: Factors important for image compression [PDF]
The use of digital mammography for breast cancer screening poses several novel problems such as development of digital sensors, computer assisted diagnosis (CAD) methods for image noise suppression, enhancement, and pattern recognition, compression ...
Blaine, G. James +7 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A high dynamic range digital LinLog CMOS image sensor architecture based on Event Readout of pixels and suitable for low voltage operation [PDF]
, 2007 Several approaches have been developed to extend the dynamic range of image sensor in order to keep all the information content of natural scenes covering a very broad range of illumination.
Guilvard, Alexandre +3 more
core
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
BrainTACO: an explorable multi-scale multi-modal brain transcriptomic and connectivity data resource
Communications BiologyExploring the relationships between genes and brain circuitry can be accelerated by joint analysis of heterogeneous datasets from 3D imaging data, anatomical data, as well as brain networks at varying scales, resolutions, and modalities.
Florian Ganglberger +7 more
doaj +1 more source