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Results 71 to 80 of about 3,365,241 (317)

Why Questions on Time-Aware Spatial Keyword Queries in Traffic Networks

IEEE Access, 2022
Time-aware spatial keyword queries in traffic networks ( $TSKQT$ ) aim to retrieve top- $k$ result objects based on the ranking score considering spatial proximity, textual relevance, and temporal similarity simultaneously. However, due to inappropriate
Xiao Jia +4 more
doaj +1 more source

151262423651567

, 2022
Source: Mapillary 4DCity URL: <a href="https://4dcity.org/imgupload/1656603339.4165.jpg">https://4dcity.org/imgupload/1656603339.4165.jpg</a> Original Image URL: <
Junior Professorship for Digital Humanities (Image/Object)
core +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source

992111608409757

, 2022
Source: Mapillary 4DCity URL: <a href="https://4dcity.org/imgupload/1656603267.747.jpg">https://4dcity.org/imgupload/1656603267.747.jpg</a> Original Image URL: <a
Junior Professorship for Digital Humanities (Image/Object)
core +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source

Non-Rigid Cycle Consistent Bidirectional Network with Transformer for Unsupervised Deformable Functional Magnetic Resonance Imaging Registration

Brain Sciences
Background: In neuroscience research about functional magnetic resonance imaging (fMRI), accurate inter-subject image registration is the basis for effective statistical analysis. Traditional fMRI registration methods are usually based on high-resolution
Yingying Wang, Yu Feng, Weiming Zeng
doaj +1 more source

1030595117666089

, 2022
Source: Mapillary 4DCity URL: <a href="https://4dcity.org/imgupload/1656603326.6979.jpg">https://4dcity.org/imgupload/1656603326.6979.jpg</a> Original Image URL: <
Junior Professorship for Digital Humanities (Image/Object)
core +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source

368271601519442

, 2022
Source: Mapillary 4DCity URL: <a href="https://4dcity.org/imgupload/1656603261.8242.jpg">https://4dcity.org/imgupload/1656603261.8242.jpg</a> Original Image URL: <
Junior Professorship for Digital Humanities (Image/Object)
core +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source

humans
radiographic image enhancement
image processing, computer-assisted

radiology information systems
3. good health
deep learning

fmri
information storage and retrieval
signal processing, computer-assisted