Results 51 to 60 of about 44,098,970 (263)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

145008397980360

, 2022
<u>Source</u>: Mapillary <br><u>4DCity URL</u>: <a href="https://4dcity.org/imgupload/1656603364.2455.jpg">https://4dcity.org/imgupload/1656603364.2455.jpg</a> <br><u>Original Image URL</u>: <
Junior Professorship for Digital Humanities (Image/Object)
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

DB-Net: A Dual-Branch Hybrid Network for Stroke Lesion Segmentation on Non-Contrast CT Images

IEEE Access
Lesion segmentation in acute ischemic stroke (AIS) is critical for accurate diagnosis, with non-contrast CT (NCCT) serving as the primary imaging modality.
Xiao Jia, He Dong, Jiashu Xu, Yanhong Zhang, Yihua Lan   +4 more
doaj   +1 more source

Improving brain tumor segmentation with anatomical prior-informed pre-training

Frontiers in Medicine, 2023
IntroductionPrecise delineation of glioblastoma in multi-parameter magnetic resonance images is pivotal for neurosurgery and subsequent treatment monitoring.
Kang Wang, Kang Wang, Zeyang Li, Haoran Wang, Haoran Wang, Siyu Liu, Siyu Liu, Mingyuan Pan, Manning Wang, Manning Wang, Shuo Wang, Shuo Wang, Zhijian Song, Zhijian Song   +13 more
doaj   +1 more source

373537400721203

, 2022
<u>Source</u>: Mapillary <br><u>4DCity URL</u>: <a href="https://4dcity.org/imgupload/1656603323.4463.jpg">https://4dcity.org/imgupload/1656603323.4463.jpg</a> <br><u>Original Image URL</u>: <
Junior Professorship for Digital Humanities (Image/Object)
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Assessment of eye fatigue caused by head-mounted displays using eye-tracking

BioMedical Engineering OnLine, 2019
Background Head-mounted displays (HMDs) and virtual reality (VR) have been frequently used in recent years, and a user’s experience and computation efficiency could be assessed by mounting eye-trackers.
Yan Wang, Guangtao Zhai, Sichao Chen, Xiongkuo Min, Zhongpai Gao, Xuefei Song   +5 more
doaj   +1 more source

488752005698388

, 2022
<u>Source</u>: Mapillary <br><u>4DCity URL</u>: <a href="https://4dcity.org/imgupload/1656603340.3632.jpg">https://4dcity.org/imgupload/1656603340.3632.jpg</a> <br><u>Original Image URL</u>: <
Junior Professorship for Digital Humanities (Image/Object)
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source