Results 81 to 90 of about 2,234,079 (295)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
A high dynamic range digital LinLog CMOS image sensor architecture based on Event Readout of pixels and suitable for low voltage operation [PDF]
, 2007 Several approaches have been developed to extend the dynamic range of image sensor in order to keep all the information content of natural scenes covering a very broad range of illumination.
Guilvard, Alexandre +3 more
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TMC4 localizes to multiple taste cell types in the mouse taste papillae
FEBS Open Bio, EarlyView.Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source
BrainTACO: an explorable multi-scale multi-modal brain transcriptomic and connectivity data resource
Communications BiologyExploring the relationships between genes and brain circuitry can be accelerated by joint analysis of heterogeneous datasets from 3D imaging data, anatomical data, as well as brain networks at varying scales, resolutions, and modalities.
Florian Ganglberger +7 more
doaj +1 more source
Digital computer processing of X-ray photos [PDF]
, 1967 Digital computers correct various distortions in medical and biological photographs. One of the principal methods of computer enhancement involves the use of a two-dimensional digital filter to modify the frequency spectrum of the picture.
Nathan, R., Selzer, R. H.
core +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Advanced Intelligent SystemsThe presence of microplastics in the environment is of significant concern, yet the exact extent of this pollution remains largely unknown. The ocean is of particular interest as the monitoring of microplastics presents a challenge in that in situ fluid ...
Fraser Montandon, Fred Nicolls
doaj +1 more source
Frontiers in Medicine, 2019 The emergence of computational pathology comes with a demand to extract more and more information from each tissue sample. Such information extraction often requires the segmentation of numerous histological objects (e.g., cell nuclei, glands, etc.) in ...
Yves-Rémi Van Eycke +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Digital Restoration of Ancient Papyri
, 2009 Image processing can be used for digital restoration of ancient papyri, that is, for a restoration performed on their digital images. The digital manipulation allows reducing the background signals and enhancing the readability of texts.
Sparavigna, Amelia
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