Results 111 to 120 of about 8,924 (230)

Identification of invisible damage in prestressed concrete bridges—A demonstrator case using coda wave interferometry

Structural Concrete, EarlyView.
Abstract During their life cycle, prestressed concrete bridges are prone to wire breaks of their tendons due to fatigue or stress corrosion cracking. However, not all structures show visible cracking on the surface, which would provide timely warning of otherwise invisible damage. Brittle failure may occur.
Noah Sträter, Felix Clauß, Mark Alexander Ahrens, Peter Mark   +3 more
wiley   +1 more source

Experimental and analytical investigations on the effect of steel fibers on the crack behavior and strength of dapped‐end connections

Structural Concrete, EarlyView.
Abstract Reinforced concrete (RC) dapped‐end connections feature a sharp re‐entrant corner subjected to high stress concentrations, leading to wide cracks under service loads and potential durability issues such as reinforcement corrosion. Effective crack control is therefore essential in the design of new dapped‐end connections. Steel fiber reinforced
Karin Yu, Sameera Hippola, Jaime Mata‐Falcón, Boyan Mihaylov   +3 more
wiley   +1 more source

Influence of shear reinforcement detailing on the shear capacity of reinforced concrete beams

Structural Concrete, EarlyView.
Abstract Alternative shear reinforcement layouts that do not fully enclose the longitudinal tensile reinforcement can significantly improve the constructability of reinforced concrete (RC) members. However, their influence on shear transfer mechanisms is not yet fully understood. To address this gap, an experimental program comprising 10 shear tests on
Franz Untermarzoner, Michael Rath, Simon Leitner, Tobias Huber, Johann Kollegger, Patrick Huber   +5 more
wiley   +1 more source

4D imaging of a porous carbonate rock under triaxial loading: quantitative correlation between local porosity and strain

Journal of Synchrotron Radiation, EarlyView.
A 4D X‐ray computed tomography experimental campaign was carried out on a porous carbonate rock to investigate the link between initial porosity and deformation modes. This paper presents the experiment and the methods used to explore this relationship.The study of the mechanical behaviour of carbonate rocks has benefited from the evolution of ...
Catherine Doré-Ossipyan, Adriana Quacquarelli, Michel Bornert, Jean Sulem, Alexandre Dimanov, Patrick Aimedieu, Vincent De Greef, Andrew King   +7 more
wiley   +1 more source

Idiographic interrater reliability measures for intensive longitudinal multirater data

British Journal of Mathematical and Statistical Psychology, EarlyView.
Abstract Interrater reliability plays a crucial role in various areas of psychology. In this article, we propose a multilevel latent time series model for intensive longitudinal data with structurally different raters (e.g., self‐reports and partner reports).
Tobias Koch, Miriam F. Jaehne, Michaela Riediger, Antje Rauers, Jana Holtmann   +4 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Non-contact strain measurement in the mouse forearm loading model using digital image correlation (DIC). [PDF]

Bone, 2015
Begonia MT, Dallas M, Vizcarra B, Liu Y, Johnson ML, Thiagarajan G.   +5 more
europepmc   +1 more source

Infrared Thermographic Assessment of Fatigue Behavior in Bolted Composite Joints

Fatigue &Fracture of Engineering Materials &Structures, EarlyView.
ABSTRACT This study investigates the temperature evolution of bolted thick glass fiber reinforced polymer composites during fatigue testing. Three different adherend thicknesses (8, 10, and 12 mm) and three different bolt tightening torques (30, 40, and 50 N·$$ \cdotp $$m were considered to evaluate the effects of adherend thickness and bolt tightening
Tolga Topkaya, Hüsna Topkaya, Murat Yavuz Solmaz   +2 more
wiley   +1 more source