Results 91 to 100 of about 831,100 (278)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Proposal for an IMLS Collection Registry and Metadata Repository [PDF]

open access: yes, 2002
The University of Illinois at Urbana-Champaign proposes to design, implement, and research a collection-level registry and item-level metadata repository service that will aggregate information about digital collections and items of digital content ...
Bennett, Nuala A.   +4 more
core  

Systemwide Clinical Ultrasound Program Development: An Expert Consensus Model. [PDF]

open access: yes, 2018
Clinical ultrasound (CUS) is integral to the practice of an increasing number of medical specialties. Guidelines are needed to ensure effective CUS utilization across health systems.
Abo, Alyssa   +19 more
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Digital Leadership and Employee Performance [PDF]

open access: yesSocial Sciences and Education Research Review
Rapid technological advancements have redefined organizational leadership, positioning digital leadership as a critical factor in enhancing employee performance.
John Olayemi OKUNLOLA
doaj   +1 more source

A leadership model for e-government transformation [PDF]

open access: yes, 2007
Since the late 1990’s governments have invested aggressively in Information and Communications Technology (ICT). This trend has paved the way for moving into the “Digital Age”.
Alshawi, S, Elnaghi, M
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Leadership, excellence, creativity and innovation [PDF]

open access: yes, 2016
Raises questions about the meaning, purpose and practice of contemporary leadership in relation to excellence, creativity and innovation, covering leadership qualities, the context and requirements of leadership, leadership at different stages of ...
Coulson-Thomas, Colin
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

A Research Framework of Digital Leadership

open access: yeseCAADe proceedings, 2018
In leading architectural offices where digital technologies have become de facto part and parcel of the architectural design process, it has become pointless to talk about ``architectural design'' and ``digital technology'' as separate phenomena. In fact, those offices showcase advances in their designs through combined developments in process, tools ...
Zupancic, Tadeja   +3 more
openaire   +3 more sources

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