Results 51 to 60 of about 831,100 (278)

Educational Leadership in the Digital Age Leadership Education in the Digital Age

Journal Coaching Education Sports, 2022
Leaders or leaders of an educational institution as people who are used to deciding what is right or most appropriate in certain situations, especially in the education policy itself. Of course, in the current era of the Industrial Revolution 4.0, policy is all about elements and values. The match is in the section itself.
Rini Andriani, Hasyim, Rahma Dewi, Afri Tantri, Nurkadri   +4 more
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Digital transformation: A model of transformational leadership in an organisation

South African Journal of Information Management
Background: Digital transformation has become essential for improving public-sector efficiency and service delivery. Despite growing investment in digital initiatives, many government entities struggle to achieve meaningful transformation. This is partly
Sello E. Mmakau, Tebogo Sethibe
doaj   +1 more source

AISR Connections, Fall 2011 (2011-2012 Orientation Issue) [PDF]

, 2011
Yearly publication of AISR Connections for 2011-2012. Issue includes: FACT Program Incorporates iPads Classroom Technologies & Videoconferencing Jefferson Digital Commons Posts Half Million Downloads The mission of Academic & Instructional Support ...
AISR,
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A situational review of national Digital Health strategy implementation in sub-Saharan Africa

The Journal for Transdisciplinary Research in Southern Africa
As the global communities approach 2030, towards achieving the United Nations (UN) Sustainable Development Goal (SDG) 3 (Good health and well-being), there are commendable technology-driven efforts in sub-Saharan Africa (SSA) to address health care ...
Oluwamayowa O. Ogundaini, Nhlanhla B.W. Mlitwa   +1 more
doaj   +1 more source

AISR Connections Fall 2012 (2012-2013 Orientation Issue) [PDF]

, 2012
Yearly publication of AISR Connections for 2012-2013. Issue includes: Scott Library renovations New library catalog Clinical Resources Support Jefferson Digital Commons The mission of Academic & Instructional Support & Resources (AISR) is to ...
AISR,
core   +1 more source

Blockchain, Leadership And Management: Business AS Usual Or Radical Disruption? [PDF]

, 2017
The Internet provided the world with interconnection. However, it did not provide it with trust. Trust is lacking everywhere in our society and is the reason for the existence of powerful intermediaries aggregating power.
Chartier-Rueg, T. C. (Theodore), Zweifel, T. D. (Thomas)   +1 more
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source