Results 191 to 200 of about 838,257 (315)
Advanced Science, EarlyView.We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang +11 more
wiley +1 more source
Effect of scan body geometric configuration and library design on digital implant impression accuracy. [PDF]
J Adv ProsthodontMoon HS, Choi A, Oh KC, Sun M, Kim J.
europepmc +1 more source
Advanced Science, EarlyView.THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu +10 more
wiley +1 more source
What's new in digital and computational pathology 2026: advances in adoption, standards, AI technologies, and clinical integration. [PDF]
J Pathol Transl MedSevim S, Hajar C, Sonawane S.
europepmc +1 more source
Advanced Science, EarlyView.Oligonucleotide‐based fluorescence in situ hybridization probes were developed in the model citrus species Citrus maxima. These probes were applied to comparative karyotyping across 14 species in the Rutaceae family. This analysis revealed chromosomal evolution in lineages that diverged from Citrus nearly 52 million years ago.
Li He +9 more
wiley +1 more source
Knowledge graph-based intelligent data management and information innovation service model for university library systems. [PDF]
PLoS OneLiu F.
europepmc +1 more source
Advanced Science, EarlyView.A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick +8 more
wiley +1 more source
Enhancing Learning Health Systems in Primary and Community Care: Contributions of NHS Library and Knowledge Specialists. [PDF]
Learn Health SystDay A, Goswami L.
europepmc +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
Synthesis of highly complex phosphorothioate-modified oligonucleotides on microarrays. [PDF]
Sci RepIlić I, Schaudy E, Lietard J.
europepmc +1 more source