Results 31 to 40 of about 92,831 (267)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Repository renewal project: a case study from White Rose Libraries

open access: yesInsights: The UKSG Journal
White Rose Libraries (WRL) is a collaboration between the university libraries of Leeds, Sheffield and York. WRL runs two shared repositories to host research outputs and electronic theses which, between them, represent one of the biggest institutional ...
Thom Blake   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Assessing the Components of Information Security in Accessing & Use of Digital Libraries

open access: yesIranian Journal of Information Processing & Management, 2021
Information security is one of the effective factors in protecting and using digital libraries which can help improve the status of these libraries.This research reviews the accessibility to information security of digital libraries in digital libraries ...
Fariborz Doroudi, Zeinab Jamshidi
doaj  

Digital Libraries and Crowdsourcing [PDF]

open access: yes, 2018
Previously, libraries already outsourced some tasks. Now, however, they can also appeal to crowds of Internet users, with whom the libraries can have a more collaborative relationship than before. These Internet users may be volunteers or paid workers, and they could be working consciously, unconsciously or in the form of games.
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Duplicate Literature Detection for Cross-Library Search

open access: yesCybernetics and Information Technologies, 2016
The proliferation of online digital libraries offers users a great opportunity to search their desired literatures on Web. Cross-library search applications can help users search more literature information from multiple digital libraries.
Liu Wei, Zeng Jianxun
doaj   +1 more source

Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms. [PDF]

open access: yesالمجلة المصرية لعلوم المعلومات
Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms.This study explores the utilization of ML content analysis algorithms to create a robust digital identity for ...
مؤمن سيد النشرتي النشرتيي
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

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