Results 41 to 50 of about 39,808,079 (300)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Repository renewal project: a case study from White Rose Libraries

Insights: The UKSG Journal
White Rose Libraries (WRL) is a collaboration between the university libraries of Leeds, Sheffield and York. WRL runs two shared repositories to host research outputs and electronic theses which, between them, represent one of the biggest institutional ...
Thom Blake, Andy Bussey, Kate Petherbridge   +2 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Access to information in digital libraries : users and digital divide [PDF]

, 2004
Recognising the importance of information and knowledge in all spheres of human life, the recently held World Summit on Information Society came up with a plan of action for building a global information society. The goal of the world information society
Chowdhury, G.
core   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Assessing the Components of Information Security in Accessing & Use of Digital Libraries

Iranian Journal of Information Processing & Management, 2021
Information security is one of the effective factors in protecting and using digital libraries which can help improve the status of these libraries.This research reviews the accessibility to information security of digital libraries in digital libraries ...
Fariborz Doroudi, Zeinab Jamshidi
doaj  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Study of Selected Digital Libraries at National Level [PDF]

, 2010
This study mainly describes various aspects of Digital Library its contents, components, characteristics, emerging technologies in Digital library.
Lihitkar, Shalini, Ghade, Vibha
core   +1 more source

Duplicate Literature Detection for Cross-Library Search

Cybernetics and Information Technologies, 2016
The proliferation of online digital libraries offers users a great opportunity to search their desired literatures on Web. Cross-library search applications can help users search more literature information from multiple digital libraries.
Liu Wei, Zeng Jianxun
doaj   +1 more source

Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms. [PDF]

المجلة المصرية لعلوم المعلومات
Creating Digital Identity for Arabic National Libraries from Content Analysis of Missions & Vision Statements Using Machine Learning Algorithms.This study explores the utilization of ML content analysis algorithms to create a robust digital identity for ...
مؤمن سيد النشرتي النشرتيي
doaj   +1 more source