Results 41 to 50 of about 37,864,627 (248)

Digital reference services : a snapshot of the current practices in scottish libraries [PDF]

open access: yes, 2004
Discusses the current practices followed by some major libraries in Scotland for providing digital reference services(DRS). Refers to the DRSs provided by three academic libraries, namely Glasgow University Library, the University of Strathclyde Library,
Chowdhury, G., Margariti, S.
core   +5 more sources

Exploring the Consistent behavior of Information Services

open access: yesMATEC Web of Conferences, 2016
Computer services are normally assumed to work well all the time. This usually happens for crucial services like bank electronic services, but not necessarily so for others, that there is no commercial interest in their operation.
Kapidakis Sarantos
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Repository renewal project: a case study from White Rose Libraries

open access: yesInsights: The UKSG Journal
White Rose Libraries (WRL) is a collaboration between the university libraries of Leeds, Sheffield and York. WRL runs two shared repositories to host research outputs and electronic theses which, between them, represent one of the biggest institutional ...
Thom Blake   +2 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Assessing the Components of Information Security in Accessing & Use of Digital Libraries

open access: yesIranian Journal of Information Processing & Management, 2021
Information security is one of the effective factors in protecting and using digital libraries which can help improve the status of these libraries.This research reviews the accessibility to information security of digital libraries in digital libraries ...
Fariborz Doroudi, Zeinab Jamshidi
doaj  

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

That's 'é' not 'þ' '?' or '☐': a user-driven context-aware approach to erroneous metadata in digital libraries [PDF]

open access: yes, 2011
In this paper we present a novel system for user-driven integration of name variants when interacting with web-based information systems. The growth and diversity of online information means that many users experience disambiguation and collocation ...
Nichols, David M.   +5 more
core   +1 more source

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