Results 221 to 230 of about 1,743,149 (359)

Accurate and Efficient Behavioral Modeling of GaN HEMTs Using An Optimized Light Gradient Boosting Machine

open access: yesAdvanced Theory and Simulations, EarlyView.
Machine Learning (ML) and optimization have permeated almost every aspect of engineering applications. Recent years have seen great traction toward ML‐based GaN HEMT modelling. However, ML‐based GaN HEMT models are mostly developed using variants of Artificial Neural Network (ANN).
Saddam Husain   +2 more
wiley   +1 more source

Guesstimation of Molecular Ensemble Electrostatics Properties Through SCERPA‐DFT Calculation: Molecular Field‐Coupled Nanocomputing as a Case Study

open access: yesAdvanced Theory and Simulations, EarlyView.
This work presents a framework combining the Self‐Consistent Electrostatic Potential Algorithm (SCERPA) and Density‐Functional Theory calculations to efficiently evaluate the electronic properties of molecular ensembles. The approach achieves ab initio‐comparable precision while significantly reducing computation time and provides the first DFT ...
Yuri Ardesi   +4 more
wiley   +1 more source

NOX2 Contributes to High‐Frequency Outer Hair Cell Vulnerability in the Cochlea

open access: yesAdvanced Science, EarlyView.
This study first identifies NOX2 as a differentially expressed gene related to oxidative damage in the apical and basal turns through single‐cell RNA sequencing. NOX2 gene knockout mitigates OHCs damage caused by neomycin and noise and enhances Nrf2 expression and nuclear translocation.
Meihao Qi   +16 more
wiley   +1 more source

Research in Support of Digital Libraries at Xerox PARC

open access: gold, 1996
Marti A. Hearst, G. Kopec, Dan Brotsky
openalex   +1 more source

Document overlap detection system for distributed digital libraries [PDF]

open access: bronze, 2000
Krisztián Monostori   +2 more
openalex   +1 more source

EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells

open access: yesAdvanced Science, EarlyView.
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li   +15 more
wiley   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

open access: yesAdvanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He   +16 more
wiley   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

open access: yesAdvanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo   +16 more
wiley   +1 more source

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