Results 271 to 280 of about 1,743,149 (359)

Development of Malaria Digital Archives in Myanmar Through Official Development Assistance and Their Narrative Review. [PDF]

Pathogens
Kanda K.
europepmc   +1 more source

Digital Libraries and the Problem of Purpose

, 2000
David M. Levy
openalex   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

Advanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen, Fushuai Peng, Shuqing Chen, Yukun Du, Jianyi Li, Yuanyuan Fan, Zichen Cui, Guanghui Gu, Han Zhang, Zhensong Jiang, Guodong Wang, Xingzhi Jing, Jun Dong, Tao Li, Yongming Xi   +14 more
wiley   +1 more source

Our Voices, Our Stories-A Multi-Method Knowledge Translation Strategy for Advancing Inclusivity and Creating Trauma-Informed Wound Care. [PDF]

Int Wound J
Costa IG, Strachan RK, Levine D, Kuper I, Santorelli S, Plazas PC, Botros M, Bajnok I, Philips C.   +8 more
europepmc   +1 more source

Research and Advanced Technology for Digital Libraries

, 2000
José Borbinha, Thomas Baker
openalex   +1 more source

Inhibiting FAT1 Blocks Metabolic Bypass to Enhance Antitumor Efficacy of TCA Cycle Inhibition through Suppressing CPT1A‐Dependent Fatty Acid Oxidation

Advanced Science, EarlyView.
This study demonstrates that mutant FAT1 promotes ASCL2‐driven, CPT1A‐dependent fatty acid oxidation, leading to resistance to CPI‐613‐mediated TCA cycle inhibition in head and neck cancer. In vivo gene depletion of mutant FAT1 with LNP‐sgFAT1 suppresses tumor growth and restores CPI‐613 sensitivity, revealing a targetable metabolic bypass with ...
Fanghui Chen, Jianqiang Yang, David O. Popoola, Fan Yang, Yajie Liu, Dongsheng Wang, Zhaohui S. Qin, Zhengjia Chen, Nabil F. Saba, Zhuo G. Chen, Yamin Li, Yong Teng   +11 more
wiley   +1 more source

PeerTECH: a randomized controlled trial of a peer-led mobile health intervention to improve medical and psychiatric self-management for persons with serious mental illness. [PDF]

Mhealth
Fortuna KL, Cui S, Lebby S, Xie H, Bruce ML, Bartels SJ.   +5 more
europepmc   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Back Talk-Print Libraries in the Digital Future

, 2000
Anthony W. Ferguson
openalex   +2 more sources

Primer‐Disk‐Enabled DNA Data Storage System with Index and Record‐Many‐Read‐Many Features

Advanced Science, EarlyView.
A primer‐disk‐enabled DNA data storage system is introduced, which allows for append‐recording of DNA files on demand, retrieval via inkjet printed QR code, and multiple ramdom read of DNA information via solid‐phase PCR. The hiearchical system with index and record‐many‐read‐many features paves the way for the practical use of DNA data storage ...
Jiaxiang Ma, Yu Yang, Ben Pei, Shengli Mi, Zhuo Xiong, Liliang Ouyang   +5 more
wiley   +1 more source