Results 21 to 30 of about 241,729 (303)
AIB Studi, 2018 Il contributo propone una riflessione sul concetto di neutralità sia in riferimento a Internet e ai motori di ricerca, sia alle biblioteche. Nella prima parte, attraverso la presentazione di esempi e il rimando ad alcuni studi sul tema, l’autrice sfata ...
Karen Coyle
doaj +1 more source
Next-Generation Data Management Plans: Global, Machine-Actionable, FAIR
International Journal of Digital Curation, 2017 At IDCC 2016 the Digital Curation Centre (DCC) and University of California Curation Center (UC3) at the California Digital Library (CDL) announced plans to merge our respective data management planning tools, DMPonline and DMPTool, into a single ...
Stephanie Renee Simms, Sarah Jones
doaj +1 more source
Data publication consensus and controversies [v2; ref status: indexed, http://f1000r.es/3hi]
F1000Research, 2014 The movement to bring datasets into the scholarly record as first class research products (validated, preserved, cited, and credited) has been inching forward for some time, but now the pace is quickening.
John Kratz, Carly Strasser
doaj +1 more source
Data publication consensus and controversies [v3; ref status: indexed, http://f1000r.es/4ja]
F1000Research, 2014 The movement to bring datasets into the scholarly record as first class research products (validated, preserved, cited, and credited) has been inching forward for some time, but now the pace is quickening.
John Kratz, Carly Strasser
doaj +1 more source
Insights: The UKSG Journal, 2017 Recognizing that academic libraries should develop and nurture strong, mutually beneficial relationships with researchers in digital humanities, the authors believe it is strategically important to invest time and resources exploring ideas and partnering
Jane Harvell, Joanna Ball
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Perspektif Allamah Tabataba’i Tentang Teori Persatuan Dalam Filsafat Agama
Kanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2013 Abstrak :Tulisan ini membahas teori persatuan dalam agama, menurut seorang filsuf dan ahli tafsir Allamah Tabataba’i. Kendati persatuan yang menjadi pembahasan pada tulisan ini adalah persatuan sosial, namun ia berbeda dengan pembahasan tentang keadilan ...
Habibullah Babai
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source