Results 31 to 40 of about 1,816,614 (312)
Managing complexity in a distributed digital library [PDF]
, 1999 As the capabilities of distributed digital libraries increase, managing organizational and software complexity becomes a key issue. How can collections and indexes be updated without impacting queries currently in progress?
Apperley, Mark +5 more
core +2 more sources
DigitalCommons@ILR Collection Development Policy [PDF]
, 2005 DigitalCommons@ILR offers electronic access to unique material that encompasses every aspect of the workplace. The Martin P. Catherwood Library provides this service as part of its ongoing mission to serve as a comprehensive information center in support
Digital Projects Group, HLM Library, Cornell University
core +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Perspektif Allamah Tabataba’i Tentang Teori Persatuan Dalam Filsafat Agama
Kanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2013 Abstrak :Tulisan ini membahas teori persatuan dalam agama, menurut seorang filsuf dan ahli tafsir Allamah Tabataba’i. Kendati persatuan yang menjadi pembahasan pada tulisan ini adalah persatuan sosial, namun ia berbeda dengan pembahasan tentang keadilan ...
Habibullah Babai
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Academic digital library in Malaysia: A case study on the status of digital reference services [PDF]
, 2010 This paper highlights the current status of digital library services provided by selected public academic libraries in Malaysia. The drift from traditional library to digital library architecture has set drastic changes in favor of adopting knowledge ...
Abdul Kadir, Razilan +1 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Por uma preservação integral da obra de arte digital: anotações sobre arte tecnológica
RDBCI: Revista Digital de Biblioteconomia e Ciência da Informação, 2016 Este trabalho reflete sobre a arte digital e a sua preservação. Como uma arte reconhecida como nativa digital (born digital), ela se encontra entre o campo da arte contemporânea e o campo amplo da tecnologia digital.
Pablo Gobira
doaj +1 more source
Open source repositories: Implications for libraries [PDF]
, 2010 Software that is accepted as “Open source” should comply with 10 conditions which are itinerated in the paper. The paper subsequently describes the application of open source initiatives in the digital library context.
A.N., Zainab
core