Results 41 to 50 of about 1,793,629 (314)

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

open access: yesMolecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa   +14 more
wiley   +1 more source

Open source repositories: Implications for libraries [PDF]

open access: yes, 2010
Software that is accepted as “Open source” should comply with 10 conditions which are itinerated in the paper. The paper subsequently describes the application of open source initiatives in the digital library context.
A.N., Zainab
core  

Sustainability for digital libraries [PDF]

open access: yes, 2004
Economic sustainability is a pressing concern for many digital library projects. One key to achieving economic sustainability is to make the digital library an integral part of its parent organisation. This can be done by having a sound product, launched
Hamilton, V.
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Developing information services for special library users by designing a low cost digital library : the experiment of NOC-Digital Library [PDF]

open access: yes, 2010
This research originates from a belief that special libraries in developing countries need to modernise and implement their ICT infrastructure and articulate information policies that will facilitate the exploitation of information resources to the ...
Elaiess, Ramadan
core   +2 more sources

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen   +5 more
wiley   +1 more source

BertSRC: transformer-based semantic relation classification

open access: yesBMC Medical Informatics and Decision Making, 2022
The relationship between biomedical entities is complex, and many of them have not yet been identified. For many biomedical research areas including drug discovery, it is of paramount importance to identify the relationships that have already been ...
Yeawon Lee, Jinseok Son, Min Song
doaj   +1 more source

York Digital Library : an ecological view of interactions and systems [PDF]

open access: yes, 2009
This case study of York Digital Library examines the development of a digital library of images at the University of York. In particular, it examines the project phase of the Fedora-based digital library and its provision of service to the History of Art
Allinson, J., Robertson, R.J.
core  

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

open access: yesAdvanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani   +4 more
wiley   +1 more source

Developing data literacy competencies to enhance faculty collaborations

open access: yesLiber Quarterly: The Journal of European Research Libraries, 2015
In order to align information literacy instruction with changing faculty and student needs, librarians must expand their skills and competencies beyond traditional information sources.
Don MacMillan
doaj   +1 more source

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