Results 41 to 50 of about 1,743,149 (359)
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Digital libraries of the future – and the role of libraries
Library Hi Tech, 2006 PurposeThe purpose of this article is to introduce the digital libraries of the future, their enabling technologies and their organisational models.Design/methodology/approachThe paper first discusses the requirements for the digital libraries of the future, then presents the DILIGENT infrastructure as a technological response to these requirements and,
openaire +5 more sources
Developing a Digital Archive with Limited Resources [PDF]
, 2004 This article describes how a small liberal arts college library created a digital library using existing staff and financial resources. The Hekman Digital Archive (HDA) was created using a digital media archive module of the library’s ILS, and is ...
Sennema, Greg
core +2 more sources
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Por uma preservação integral da obra de arte digital: anotações sobre arte tecnológica
RDBCI: Revista Digital de Biblioteconomia e Ciência da Informação, 2016 Este trabalho reflete sobre a arte digital e a sua preservação. Como uma arte reconhecida como nativa digital (born digital), ela se encontra entre o campo da arte contemporânea e o campo amplo da tecnologia digital.
Pablo Gobira
doaj +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
Academic digital library in Malaysia: A case study on the status of digital reference services [PDF]
, 2010 This paper highlights the current status of digital library services provided by selected public academic libraries in Malaysia. The drift from traditional library to digital library architecture has set drastic changes in favor of adopting knowledge ...
Abdul Kadir, Razilan +1 more
core
Molecular Oncology, EarlyView.Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh +5 more
wiley +1 more source
BertSRC: transformer-based semantic relation classification
BMC Medical Informatics and Decision Making, 2022 The relationship between biomedical entities is complex, and many of them have not yet been identified. For many biomedical research areas including drug discovery, it is of paramount importance to identify the relationships that have already been ...
Yeawon Lee, Jinseok Son, Min Song
doaj +1 more source