Results 41 to 50 of about 1,868,549 (314)

Why we need to find time for digital humanities: presenting a new partnership model at the University of Sussex

Insights: The UKSG Journal, 2017
Recognizing that academic libraries should develop and nurture strong, mutually beneficial relationships with researchers in digital humanities, the authors believe it is strategically important to invest time and resources exploring ideas and partnering
Jane Harvell, Joanna Ball
doaj   +1 more source

DigitalCommons@ILR Collection Development Policy [PDF]

, 2005
DigitalCommons@ILR offers electronic access to unique material that encompasses every aspect of the workplace. The Martin P. Catherwood Library provides this service as part of its ongoing mission to serve as a comprehensive information center in support
Digital Projects Group, HLM Library, Cornell University
core   +1 more source

Sustainability for digital libraries [PDF]

, 2004
Economic sustainability is a pressing concern for many digital library projects. One key to achieving economic sustainability is to make the digital library an integral part of its parent organisation. This can be done by having a sound product, launched
Hamilton, V.
core   +2 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Perspektif Allamah Tabataba’i Tentang Teori Persatuan Dalam Filsafat Agama

Kanz Philosophia: A Journal for Islamic Philosophy and Mysticism, 2013
Abstrak :Tulisan ini membahas teori persatuan dalam agama, menurut seorang filsuf dan ahli tafsir Allamah Tabataba’i. Kendati persatuan yang menjadi pembahasan pada tulisan ini adalah persatuan sosial, namun ia berbeda dengan pembahasan tentang keadilan ...
Habibullah Babai
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Academic digital library in Malaysia: A case study on the status of digital reference services [PDF]

, 2010
This paper highlights the current status of digital library services provided by selected public academic libraries in Malaysia. The drift from traditional library to digital library architecture has set drastic changes in favor of adopting knowledge ...
Abdul Kadir, Razilan, Wan Dollah, Wan Ab. Kadir   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Por uma preservação integral da obra de arte digital: anotações sobre arte tecnológica

RDBCI: Revista Digital de Biblioteconomia e Ciência da Informação, 2016
Este trabalho reflete sobre a arte digital e a sua preservação. Como uma arte reconhecida como nativa digital (born digital), ela se encontra entre o campo da arte contemporânea e o campo amplo da tecnologia digital.
Pablo Gobira
doaj   +1 more source