Results 341 to 350 of about 3,320,974 (419)

Investigating Dopamine Replacement–Associated Fluctuations in Cognition and Mood in Cognitively Unimpaired Parkinson's Disease

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Non‐motor fluctuations, characterized by variability in mood and cognition, are prevalent in advanced Parkinson's disease (PD), but less is known about these fluctuations in early PD. Objective The objective was to characterize fluctuations in cognition and mood in early PD without cognitive impairment.
Abhimanyu Mahajan   +4 more
wiley   +1 more source

Differences in Parkinson's Disease Populations: Teaching Hospitals Versus Other Settings and Implications for Clinical Trials

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson disease (PD) disease‐modifying therapy (DMT) trials generally recruit individuals from teaching hospitals. Whether these participants represent the broader PD population is unclear. Objective The objective was to compare individuals with PD seen by neurologists in teaching hospitals early in their disease—a proxy for DMT ...
Priti Gros   +6 more
wiley   +1 more source

Sex and Racial/Ethnic Differences in End‐of‐Life Care Preferences in Persons with Parkinson's Disease and Related Disorders

open access: yesMovement Disorders, EarlyView.
Abstract Background In persons with Parkinson's disease (PD) and related disorders (PDRD), rates of end‐of‐life (EoL) hospitalization are greatest, and rates of hospice utilization lowest, among men and persons of color. Reasons for these differences are unknown.
Whitley W. Aamodt   +7 more
wiley   +1 more source

Enhancing Heart Health: Expanding the Use of SGLT2 Inhibitors in Cardiovascular Disease

open access: yesMedicine Advances, EarlyView.
SGLT2 inhibitors offer multifaceted cardiovascular benefits, including improved cardiac metabolism, reduced preload and afterload, and decreased myocardial infarction risk. These effects are driven by renoprotection, anti‐inflammatory properties, improved mitochondrial function, osmotic diuresis, and glycemic control. Together, these mechanisms support
Manahil Mubeen   +3 more
wiley   +1 more source

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