Results 41 to 50 of about 1,327,891 (307)

Digitalised Responses: Understanding the Digital Literary Spaces in the Light of Keshava Guha’s Accidental Magic

IAFOR Journal of Arts & Humanities, 2023
Literature was quick to respond to emerging digital technologies in the late 1990s. Fiction writing and publishing took to the Internet, although traditional methods of print publication largely remained in place.
Sapphire Mahmood Ahmed, K. Rizwana Sultana   +1 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Waves of Pixels and Word-generated Algorithms: Drone Poetry as a Collaborative Practice between Machine and Human in Waveform by Richard A. Carter

Text Matters, 2023
The following article explores the creative collaborative practices in digital poetry between more-than-human agents. Richard A. Carter’s artistic project Waveform (2017–) makes one reconsider the ways in which multimodal and web-based encounters of ...
Katarzyna Ostalska
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Hacking Literature: Reading Analog Texts in a Digital Age [PDF]

, 2014
Evangelists of the digital age, in the immediacy of its adolescence, often describe digital technologies as "revolutionary" (e.g. "the digital revolution") and as having a world-changing impact on human cultural interactions.
Dinin, Aaron
core  

Platform Writers and the Production of Digital Literature: The Professionalism of Female Pesantren Novelists in Indonesia

International Quarterly for Asian Studies
The new global genres of “chick lit” and “teen lit” in the early twenty-first century led to the rise of a new generation of Muslim women writers in Indonesia.
Nor Ismah
doaj   +1 more source

Estudos literários digitais: projetos, métodos, ferramentas

MatLit, 2016
Brief presentation of eight websites related to Digital Literary Studies. The selection is intended to be a sample of projects, methods and digital tools, including anthologies of digital literature and digital literary studies, media archaeology ...
Ministro, Bruno
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

La « dimension argumentative » plurisémiotique du livre enrichi

Argumentation et Analyse du Discours, 2018
The case study of this paper are two enhanced books: Beauvoir, l’enquête, by Irène Frain, and Alienare, by Chloé Delaume. The rhetoric of the digital text is essential to the study of the relationship between Frain’s and Delaume’s “author’s image”  and ...
Sara Amadori
doaj   +1 more source

Web : effets de l’hybridation des pratiques littéraires sur la transtextualité des écritures numériques, la « rhizotextualité » à l’œuvre chez Pierre Ménard

Recherches & Travaux, 2022
The hybridization of literary and digital practices leads digital writings to acquire specificities as well as a strong performativity that can be deployed both on and off the screen.
Karen Cayrat
doaj   +1 more source