Results 31 to 40 of about 84,502 (290)

Industrial Insights on Digital Twins in Manufacturing: Application Landscape, Current Practices, and Future Needs

Big Data and Cognitive Computing, 2023
The digital twin (DT) research field is experiencing rapid expansion; yet, the research on industrial practices in this area remains poorly understood.
Rosario Davide D’Amico, Sri Addepalli, John Ahmet Erkoyuncu   +2 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Impact of adopting industry 4.0 practices and technologies on time and motion study: a pilot study revealing efficiency gains in a multi-operation workstation

Production and Manufacturing Research: An Open Access Journal
This article presents a time and motion study tool, that migrate from a descriptive approach to one based on data analysis. It presents the engineering design, its application, the analysis of the results obtained in a pilot study, the results of the ...
Cristiano Jesus, Ivan Amorim, Eduardo Pontes, Sandra Gonçalves, Azin Moradbeikie, Sérgio Lopes   +5 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

One-Step Mask-Based Diffraction Lithography for the Fabrication of 3D Suspended Structures

Nanoscale Research Letters, 2018
We propose a novel one-step exposure method for fabricating three-dimensional (3D) suspended structures, utilizing the diffraction of mask patterns with small line width.
Xianhua Tan, Tielin Shi, Jianbin Lin, Bo Sun, Zirong Tang, Guanglan Liao   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Modification of the AFM Sensor by a Precisely Regulated Air Stream to Increase Imaging Speed and Accuracy in the Contact Mode

Sensors, 2018
Increasing the imaging rate of atomic force microscopy (AFM) without impairing of the imaging quality is a challenging task, since the increase in the scanning speed leads to a number of artifacts related to the limited mechanical bandwidth of the AFM ...
Andrius Dzedzickis, Vytautas Bucinskas, Darius Viržonis, Nikolaj Sesok, Arturas Ulcinas, Igor Iljin, Ernestas Sutinys, Sigitas Petkevicius, Justinas Gargasas, Inga Morkvenaite-Vilkonciene   +9 more
doaj   +1 more source

Integrated Planning and Scheduling of Multiple Manufacturing Projects Under Resource Constraints Using Raccoon Family Optimization Algorithm

IEEE Access, 2020
Today's dynamic environment and increasing demand for highly customized products have significantly increased the number of companies operating in the project environment.
Mudassar Rauf, Zailin Guan, Lei Yue, Ziteng Guo, Jabir Mumtaz, Saif Ullah   +5 more
doaj   +1 more source

In Situ Filler Addition for Homogeneous Dispersion of Carbon Nanotubes in Multi Jet Fusion–Printed Elastomer Composites

Advanced Science, 2023
The dispersibility of fillers determines their effect on the mechanical properties and anisotropy of the 3D‐printed polymeric composites. Nanoscale fillers have the tendency to aggregate, resulting in the deterioration of part performance.
Jiayao Chen, Ran An, Wei Shian Tey, Qingyun Zeng, Lihua Zhao, Kun Zhou   +5 more
doaj   +1 more source