Results 201 to 210 of about 17,520 (245)
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Digital Microfluidics for Immunoprecipitation
Analytical Chemistry, 2016Immunoprecipitation (IP) is a common method for isolating a targeted protein from a complex sample such as blood, serum, or cell lysate. In particular, IP is often used as the primary means of target purification for the analysis by mass spectrometry of novel biologically derived pharmaceuticals, with particular utility for the identification of ...
Brendon, Seale +5 more
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Digital microfluidic meter-on-chip
Lab on a Chip, 2020On-chip digital microfluidic flowmetry can be designed and incorporated into standard microfluidic devices for high-precision multiplexed microflow measurements.
Zecong Fang +6 more
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A digital microfluidic electrochemical immunoassay
Lab Chip, 2014Digital microfluidics (DMF) has emerged as a popular format for implementing quantitative immunoassays for diagnostic biomarkers. All previous reports of such assays have relied on optical detection; here, we introduce the first digital microfluidic immunoassay relying on electrochemical detection.
Mohtashim H, Shamsi +3 more
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Machine vision for digital microfluidics
Review of Scientific Instruments, 2010Machine vision is widely used in an industrial environment today. It can perform various tasks, such as inspecting and controlling production processes, that may require humanlike intelligence. The importance of imaging technology for biological research or medical diagnosis is greater than ever.
Yong-Jun, Shin, Jeong-Bong, Lee
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Digital microfluidics for biological analysis and applications
Lab on a Chip, 2023Digital microfluidic (DMF) bioassays with the benefits of automation, addressability, integration and dynamic configuration ability for nucleic acids, proteins, immunoreaction and cell analysis are presented in this review.
Xing Xu +9 more
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Velocity Saturation in Digital Microfluidics
Langmuir, 2019In digital microfluidics, discrete droplets of fluid are made to move on an open surface with no microchannels. These systems are commonly operated by application of electrical driving forces to an array of electrodes. While these driving forces are well characterized, the dissipative forces opposing droplet movement have not been as thoroughly ...
Ian Swyer, Ryan Fobel, Aaron R. Wheeler
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2014
Electromechanically driven fluid displacement over solid surfaces has significant advantages over bulk flow regimes, particularly when the fluid volume is in the form of a droplet. Voltage-induced interfacial surface tension alterations at the unbound surface of a droplet increase the droplets' wettability over a hydrophobic surface. This phenomenon is
Kailiang Wang, Henry O. Fatoyinbo
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Electromechanically driven fluid displacement over solid surfaces has significant advantages over bulk flow regimes, particularly when the fluid volume is in the form of a droplet. Voltage-induced interfacial surface tension alterations at the unbound surface of a droplet increase the droplets' wettability over a hydrophobic surface. This phenomenon is
Kailiang Wang, Henry O. Fatoyinbo
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Additive-Free Digital Microfluidics
Langmuir, 2013Digital microfluidics, a technique for manipulation of droplets, is becoming increasingly important for the development of miniaturized platforms for laboratory processes. Despite the enthusiasm, droplet motion is frequently hindered by the desorption of proteins or other analytes to surfaces.
Sergio L S, Freire, Brendan, Tanner
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Digital Microfluidic Cell Culture
Annual Review of Biomedical Engineering, 2015Digital microfluidics (DMF) is a droplet-based liquid-handling technology that has recently become popular for cell culture and analysis. In DMF, picoliter- to microliter-sized droplets are manipulated on a planar surface using electric fields, thus enabling software-reconfigurable operations on individual droplets, such as move, merge, split, and ...
Alphonsus H C, Ng +3 more
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Democratizing Digital Microfluidics
2021 21st International Conference on Solid-State Sensors, Actuators and Microsystems (Transducers), 2021As a subset of microfluidics, digital microfluidics handles fluids as small discrete entities (e.g., droplets) by actuating them individually. The choice of actuation mechanism to handle droplets has been electrowetting, especially in the form of electrowetting-on-dielectric (EWOD) developed in early 2000s.
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