Results 291 to 300 of about 2,871,670 (306)

Vertical Addressing of 1‐Plane Electrodes for Digital Microfluidics

Advanced Materials & Technologies, 2021
Digital microfluidics (DMF) has become a mainstay in the microfluidics and microelectromechanical communities. Many users rely on simple DMF devices featuring a small number of rows and columns of electrodes that can be rapidly manufactured using “one ...
Sebastian von der Ecken, Alexandros A. Sklavounos, A. R. Wheeler   +2 more
semanticscholar   +1 more source

Democratizing Digital Microfluidics

International Conference on Solid-State Sensors, Actuators and Microsystems, 2021
As a subset of microfluidics, digital microfluidics handles fluids as small discrete entities (e.g., droplets) by actuating them individually. The choice of actuation mechanism to handle droplets has been electrowetting, especially in the form of ...
C. Kim
semanticscholar   +1 more source

A Highly Sensitive, Accurate and Automated Single-cell RNA Sequencing Platform with Digital Microfluidics.

Analytical Chemistry, 2020
Single-cell RNA sequencing (scRNA-seq) is a powerful method in investigating single-cell heterogeneity to reveal rare cells, identify cell subpopulations and construct a cell atlas.
Xing Xu, Qianqian Zhang, Jia Song, Qingyu Ruan, Weidong Ruan, Yujie Chen, Jian Yang, Xuebing Zhang, Yanling Song, Zhi Zhu, C. Yang   +10 more
semanticscholar   +1 more source

Large-area manufacturable active matrix digital microfluidics platform for high-throughput biosample handling

International Electron Devices Meeting, 2020
We present an active-matrix digital microfluidics platform for bio-sample handling, which demonstrates extension of the ubiquitous and highly-scalable flat-panel technology from displays to bio-applications, and leverage the well-established a-Si thin ...
H. Ma, S. Shi, K. Jin, D. Wang, S. Hu, Y. Su, Y. Zhang, J. Li, Z. Liu, C. Jiang, L. Feng, X. Guo, A. Nathan   +12 more
semanticscholar   +1 more source

Turning on/off satellite droplet ejection for flexible sample delivery on digital microfluidics.

Lab on a Chip, 2020
Digital microfluidics has the potential to minimize and automate reactions in biochemical labs. However, the complexity of drop manipulation and sample preparation on-chip has limited its incorporation into daily workflow.
Haoran Li, Ren Shen, Cheng Dong, Tianlan Chen, Yanwei Jia, Pui-in Mak, R. Martins   +6 more
semanticscholar   +1 more source

"Plug-n-Play" Sensing with Digital Microfluidics.

Analytical Chemistry, 2019
Digital microfluidics (DMF) is a platform that enables highly reconfigurable and automated fluidic operations using a generic device architecture. A unique hallmark of DMF is its "flexibility": a generic device design can be used and reused for many ...
R. P. D. de Campos, Darius G. Rackus, R. Shih, Chen Zhao, Xinyu Liu, A. R. Wheeler   +5 more
semanticscholar   +1 more source

Magnetic Digital Microfluidics for Point-of-Care Testing: Where Are We Now?

Current Medicinal Chemistry, 2020
Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis.
Yi Zhang
semanticscholar   +1 more source

Rapid Chemical Reaction Monitoring by Digital Microfluidics-NMR: Proof of Principle Towards an Automated Synthetic Discovery Platform.

Angewandte Chemie, 2019
Microcoil Nuclear magnetic resonance (NMR) has been interfaced with digital microfluidics (DMF) and is applied to monitor organic reactions in organic solvents as a proof of concept.
Bing Wu, S. Ecken, Ian Swyer, Chunliang Li, A. Jenne, F. Vincent, Daniel Schmidig, Till Kuehn, Armin Beck, F. Busse, H. Stronks, R. Soong, A. R. Wheeler, A. Simpson   +13 more
semanticscholar   +1 more source

Miniaturized sample preparation on a digital microfluidics device for sensitive bottom-up microproteomics of mammalian cells using magnetic beads and mass spectrometry-compatible surfactants.

Lab on a Chip, 2019
While LC-MS-based proteomics with high nanograms to micrograms of total protein has become routine, the analysis of samples derived from low cell numbers is challenged by factors such as sample losses, or difficulties encountered with the manual ...
Jan Leipert, A. Tholey
semanticscholar   +1 more source

Antifouling digital microfluidics using lubricant infused porous film.

Lab on a Chip, 2019
Electrowetting-driven digital (droplet-based) microfluidics has a tremendous impact on lab-on-a-chip applications. However, the biofouling problem impedes the real applications of such digital microfluidics.
Hongyao Geng, S. Cho
semanticscholar   +1 more source