Results 61 to 70 of about 4,109,115 (314)

A simple model of EMI-induced timing jitter in digital circuits, its statistical distribution and its effect on circuit performance [PDF]

, 2003
A simple model has been developed to characterize electromagnetic interference induced timing variations (jitter) in digital circuits. The model is based on measurable switching parameters of logic gates, and requires no knowledge of the internal ...
Fischer, K., Flintoft, I.D., Marvin, A.C., Robinson, M.P.   +3 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

High-Speed Communications Over Polymer Optical Fibers for In-Building Cabling and Home Networking [PDF]

, 2010
This paper focuses on high-speed cabling using polymer optical fibers (POF) in home networking. In particular, we report about the results obtained in the POF-ALL European Project, which is relevant to the Sixth Framework Program, and after two years of ...
Abrate, S., Gaudino, Roberto, Nespola, A., Offenbeck, B., Weber, N., Zerna, C.   +5 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Single Photon Compressive Imaging Based on Digital Grayscale Modulation Method

Photonic Sensors, 2020
In single-pixel imaging or computational ghost imaging, the measurement matrix has a great impact on the performance of the imaging system, because it involves modulation of the optical signal and image reconstruction.
Chenglong Yuan, Qiurong Yan, Yiqiang Wu, Yifan Wang, Yuhao Wang   +4 more
doaj   +1 more source

Digital phase-modulation/multiplex system [PDF]

, 1970
System combines and modulates subcarriers and pulse code modulation data entirely with digital logic, and phase modulates an RF carrier with a digital representation of the composite subcarrier signal.
Couvillon, L. A.
core   +1 more source

Improving the chromatic dispersion tolerance in long-haul fibre links using the coherent optical orthogonal frequency division multiplexing [PDF]

, 2010
Numerical simulations of the coherent optical orthogonal frequency division multiplexing modems are undertaken to investigate the effect of the adaptive modulation, the number of sub-carriers, the cyclic prefix (CP) length, the clipping ratio ...
Brendon, Cavallari, Färbert, Giacoumidis, Hellerbrand, Jansen, Lowery, Lowery, Lowery, Lowery, Ly-Gagnon, M.A. Jarajreh, Roberts, Shieh, Shieh, Shieh, Simeone, Tanaka, Tang, W.P. Ng, Weber, Z. Ghassemlooy   +21 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Method of Non-Data-Aided Carrier Recovery with Modulation Identification [PDF]

, 2004
A non-data aided carrier recovery technique using digital modulation format identification called multi-mode PLL (Phase Locked Loop) is proposed. This technique can be interpreted as a modulation identification method that is robust against static phase ...
Kohno, Ryuji, Morelos-Zaragoza, Robert H, Umebayashi, Kenta   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source