Results 131 to 140 of about 43,201,948 (340)

Applications of Digital Pathology in Cancer: A Comprehensive Review

Annual Review of Cancer Biology
Digital pathology, powered by whole-slide imaging technology, has the potential to transform the landscape of cancer research and diagnosis. By converting traditional histopathological specimens into high-resolution digital images, it paves the way for ...
Mohamed Omar, Mohammad K Alexanderani, Itzel Valencia, M. Loda, L. Marchionni   +4 more
semanticscholar   +1 more source

Four‐Year Cognitive Outcomes in Multiple Sclerosis: Associations With Lesion Myelin Integrity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Cognitive impairment is prevalent in patients with multiple sclerosis (MS) but whether lesion myelin integrity influences future cognitive outcomes remains unclear. We investigated the relationship between baseline lesion myelin water fraction (MWF) and cognitive performance 4 years later.
Iliana Pliska‐Bloch, Hannah Schwartz, Kimberly H. Markowitz, Abhishek Jaywant, Christopher D. Hildenbrand, Jai Perumal, Ulrike W. Kaunzner, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Clinician Perspectives on Digital and Computational Pathology: Clinical Benefits, Concerns, and Willingness to Adopt

Diagnostics
Background/Objectives: Precision medicine has transformed how we manage cancer patients. As treatments and drug targets become more complex, the associated diagnostic technologies must also evolve to actualize the benefit of these therapeutic innovations.
Charu Aggarwal, Aakash Desai, Nicholas McConnell, Nicholas Cadirov, Gary Gustavsen, Arushi Agarwal, Nabil Chehab, Srividya Kotapati, Nikunj Patel   +8 more
doaj   +1 more source

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Artificial intelligence in digital pathology: Principles, applications, challenges, and future directions

Journal of Pathology Informatics
This article provides an overview of digital pathology and its evolving role in modern diagnostic practice. We begin by comparing conventional microscopy with digital pathology and outlining the major components of the digital pathology workflow. We then
Yifei Wang, Leona Odabachian
doaj   +1 more source

Digital pathology, deep learning, and cancer: a narrative review

medRxiv
Background and Objective: Cancer is a leading cause of morbidity and mortality worldwide. The emergence of digital pathology and deep learning technologies signifies a transformative era in healthcare.
Darnell K. Adrian Williams, Gillian Graifman, Nowair Hussain, Maytal Amiel, Priscilla Tran, A. Reddy, Ali Haider, Bali Kumar Kavitesh, Austin Li, Leael Alishahian, Nichelle Perera, Corey Efros, Myoungmee Babu, M. Tharakan, Mill Etienne, B. Babu   +15 more
semanticscholar   +1 more source

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Crossing the Andes: Challenges and opportunities for digital pathology in Latin America

Journal of Pathology Informatics
The most widely accepted and used type of digital pathology (DP) is whole-slide imaging (WSI). The USFDA granted two WSI system approvals for primary diagnosis, the first in 2017.
R. Coudry, Emilio Assis, F. Frassetto, A. M. Jansen, L. M. da Silva, R. Parra-Medina, M. Saieg   +6 more
semanticscholar   +1 more source

Beyond Visual Scoring: Computational Computed Tomography Analysis for High‐Resolution Computed Tomography–Based Quantification of Interstitial Lung Disease in Inflammatory Rheumatic Disease

Arthritis Care &Research, EarlyView.
Interstitial lung disease (ILD) is a significant cause of morbidity and mortality in patients with inflammatory rheumatic disorders (IRDs). High‐resolution computed tomography (HRCT) is widely considered the gold standard for the noninvasive assessment of ILD; however, its interpretation is constrained by substantial interobserver variability and the ...
Alexander Pfeil, Tobias Hoffmann, Ulf Teichgräber, Diane Renz, Denise Beckmann, Gunter Wolf, Nicole Schadewaldt, Bianca Lassen‐Schmidt   +7 more
wiley   +1 more source