Results 161 to 170 of about 256,462 (249)

Lessons learned from three approaches to digital pathology system validation at a large academic medical institution. [PDF]

J Pathol Inform
Krishnan T, Garrett J, Henriksen J, Zhen D, Gonzalez-Cuyar L, Hosny K.   +5 more
europepmc   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

The Augmented Cytopathologist: A Conceptual Exploratory Narrative Review on Immersive and Vision-Language Models Tools in Digital Pathology. [PDF]

J Imaging
Giarnieri E, Lastrucci A, Ricci A, Bruno P, Giansanti D.   +4 more
europepmc   +1 more source

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Adaptive example selection for prototype based explainable mitosis detection in digital pathology. [PDF]

Sci Rep
Banik M, Kreutz-Delgado K, Mohanty I, Brown JB, Singh N.   +4 more
europepmc   +1 more source

Wireless, Deep‐Seeing Smart Pill: A NIR‐II Fluorescence Imaging Capsule Endoscope for Gastrointestinal Cancer

Advanced Science, EarlyView.
A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang, Jinlei Jiang, Zhengting Wang, Shuqi Liu, Wei Wang, Xi Chen, Qirui Zhao, Xinyuan Cui, Cheng Zhou, Shengsheng Cui, Daxiang Cui   +10 more
wiley   +1 more source

Double Staining Immunohistochemistry and Digital Pathology: Moving Towards Standardization of the Proliferative Index Evaluation in Meningiomas. [PDF]

J Pers Med
Fabbri VP, Broggi G, Attolini G, L'Imperio V, Pagni F, Guerriero A, Marletta S, Fiorentino F, Caramaschi S, Malagoli C, Eccher A, Caltabiano R.   +11 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Color Management in Digital Pathology

Analytical Cellular Pathology, 2014
W. Craig Revie, Mike Shires, Pete Jackson, David Brettle, Ravinder Cochrane, Darren Treanor   +5 more
doaj   +1 more source

Digital Pathology Standards: A Response to WG-26. [PDF]

J Pathol Inform
Gershkovich P.
europepmc   +1 more source