Results 41 to 50 of about 515,047 (278)

The future of laboratory medicine - A 2014 perspective. [PDF]

open access: yes, 2015
Predicting the future is a difficult task. Not surprisingly, there are many examples and assumptions that have proved to be wrong. This review surveys the many predictions, beginning in 1887, about the future of laboratory medicine and its sub ...
FORTINA, PAOLO   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Going fully digital: Perspective of a Dutch academic pathology lab

open access: yesJournal of Pathology Informatics, 2013
During the last years, whole slide imaging has become more affordable and widely accepted in pathology labs. Digital slides are increasingly being used for digital archiving of routinely produced clinical slides, remote consultation and tumor boards, and
Nikolas Stathonikos   +3 more
doaj   +1 more source

The ethical challenges of artificial intelligence‐driven digital pathology

open access: yesThe Journal of Pathology: Clinical Research, 2022
Digital pathology – the digitalisation of clinical histopathology services through the scanning and storage of pathology slides – has opened up new possibilities for health care in recent years, particularly in the opportunities it brings for artificial ...
Francis McKay   +5 more
doaj   +1 more source

Challenges in implementing a digital pathology workflow in surgical pathology

open access: yesHuman Pathology Reports, 2022
The rate of digital pathology adoption had been slow until the COVID-19 pandemic served as catalyst, demonstrating the possibilities of saving time and money by converting glass slides into whole slide images (WSI) and thus making them available to all ...
Giovani Lujan, Zaibo Li, Anil V. Parwani
doaj   +1 more source

Classification and Retrieval of Digital Pathology Scans: A New Dataset

open access: yes, 2017
In this paper, we introduce a new dataset, \textbf{Kimia Path24}, for image classification and retrieval in digital pathology. We use the whole scan images of 24 different tissue textures to generate 1,325 test patches of size 1000$\times$1000 (0.5mm ...
Babaie, Morteza   +7 more
core   +1 more source

Aspergillus fumigatus preexposure worsens pathology and improves control of Mycobacterium abscessus pulmonary infection in mice [PDF]

open access: yes, 2018
Cystic fibrosis (CF) is an autosomal recessive disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Mutations in this chloride channel lead to mucus accumulation, subsequent recurrent pulmonary infections, and ...
Elsegeiny, Waleed   +7 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Understanding the financial aspects of digital pathology: A dynamic customizable return on investment calculator for informed decision-making

open access: yesJournal of Pathology Informatics
Background: The adoption of digital pathology has transformed the field of pathology, however, the economic impact and cost analysis of implementing digital pathology solutions remain a critical consideration for institutions to justify.
Orly Ardon   +10 more
doaj   +1 more source

Banff Digital Pathology Working Group: Image Bank, Artificial Intelligence Algorithm, and Challenge Trial Developments

open access: yesTransplant International, 2023
The Banff Digital Pathology Working Group (DPWG) was established with the goal to establish a digital pathology repository; develop, validate, and share models for image analysis; and foster collaborations using regular videoconferencing.
Alton B. Farris   +27 more
doaj   +1 more source

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