Results 61 to 70 of about 538,097 (282)
TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy [PDF]
, 2017 Significance Alzheimer’s disease (AD) is the most common cause of dementia and is a major public health problem for which there is currently no disease-modifying treatment.
Anderson, Elise +9 more
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Transplant International, 2023 The Banff Digital Pathology Working Group (DPWG) was established with the goal to establish a digital pathology repository; develop, validate, and share models for image analysis; and foster collaborations using regular videoconferencing.
Alton B. Farris +27 more
doaj +1 more source
Validation of machine learning models to detect amyloid pathologies across institutions. [PDF]
, 2020 Semi-quantitative scoring schemes like the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) are the most commonly used method in Alzheimer's disease (AD) neuropathology practice.
Dugger, Brittany N +5 more
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Journal of Pathology InformaticsBackground: The adoption of digital pathology has transformed the field of pathology, however, the economic impact and cost analysis of implementing digital pathology solutions remain a critical consideration for institutions to justify.
Orly Ardon +10 more
doaj +1 more source
The Role and Financial Implications of Digital Pathology for the System Health [PDF]
Ovidius University Annals: Economic Sciences Series, 2020 Public health system is under great pressure to cope with old and new threats which can have different causes. Progresses regarding methods of diagnosis and treatment options pushed the pathology filed to move forward.
Gabriela Izabela Băltățescu +2 more
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Expanding application of digital pathology in Japan - from education, telepathology to autodiagnosis
Diagnostic Pathology, 2011 Background Digital pathology, i.e., applications of digital information technologies to pathology practice, has been expanding in the recent decades and the mode of pathology diagnostic practice is changing with enhanced precision.
Tsuchihashi Yasunari
doaj +1 more source
Summary of the 4th nordic symposium on digital pathology
Journal of Pathology Informatics, 2017 The Nordic symposium on digital pathology (NDP) was created to promote knowledge exchange across stakeholders in health care, industry, and academia.
Claes Lundström +3 more
doaj +1 more source