Results 71 to 80 of about 515,047 (278)
Academic Pathology, 2021 Implementation of an infrastructure to support digital pathology began in 2006 at Memorial Sloan Kettering Cancer Center. The public health emergency and COVID-19 pandemic regulations in New York City required a novel workflow to sustain existing ...
Orly Ardon PhD, MBA +11 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Updates in ophthalmic pathology
Indian Journal of Ophthalmology, 2017 Ophthalmic pathology has a long history and rich heritage in the field of ophthalmology. This review article highlights updates in ophthalmic pathology that have developed significantly through the years because of the efforts of committed individuals ...
Pia R Mendoza, Hans E Grossniklaus
doaj +1 more source
Метод визуализации патологических структур на маммограммах [PDF]
, 2013 Рассмотрены методы цифровой фильтрации маммограмм. Определены особенности влияния различных видов фильтров на методы нахождения границ патологий на маммограммах.
Бойко, Д. А. +1 more
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The 1 million words pathology report or the challenge of a reproducible and meaningful message
ESMO Real World Data and Digital OncologyMany years have passed since the pathology report was all about a single-sentence diagnosis based on morphology. The pathology report is an invaluable source of data that needs to evolve from a narrative reporting to a synoptic reporting system by ...
C. Eloy +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Playing public health: building the HIVe [PDF]
, 2012 In thinking through the impact of digital media on how frontline workers, activists, practitioners and researchers understand and fight HIV and AIDS, it is important to acknowledge that digital media does not only provide new channels and strategies for ...
Apperley, Thomas, Walsh, Christopher S.
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Using World-Wide-Web technology for pathology education [PDF]
, 1997 In this article, we describe the development of computer-based learning programs for pathology students at Jefferson Medical College. These programs are authored using HTML (HyperText Markup Language), and are available to students on campus and via the ...
Braster, Christopher D +3 more
core +1 more source