Results 41 to 50 of about 950,229 (283)

The Digital Platform, Enterprise Digital Transformation, and Enterprise Performance of Cross-Border E-Commerce—From the Perspective of Digital Transformation and Data Elements

Journal of Theoretical and Applied Electronic Commerce Research, 2023
The digital trade ecosystem’s development relies on the growth of cross-border e-commerce platforms. To ensure the continued growth of China’s digital trade, it is crucial to consider the service capabilities of digital platforms and the digital ...
Yunpeng Yang, Nan Chen, Hongmin Chen
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Digital Manufacturing Platforms in the Industry 4.0 from Private and Public Perspectives

Applied Sciences, 2019
The fourth industrial revolution is characterized by the introduction of the Internet of things (IoT) and Internet of Services (IoS) concepts into manufacturing, which enables smart factories with vertically and horizontally integrated production systems.
Jon Kepa Gerrikagoitia, Gorka Unamuno, Elena Urkia, Ainhoa Serna   +3 more
doaj   +1 more source

THE UTILIZATION OF DIGITAL PLATFORMS IN ONLINE LEARNING: EFL STUDENTS’ PERSPECTIVES

Indonesian EFL Journal, 2021
The purpose of this research was to investigate the EFL students’ perspectives toward the utilization of digital platforms in online learning. Learning Management System, WhatsApp, and Google Meet are the digital platforms used in the online learning ...
Ira Irzawati
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Recent Advances in Superhydrophobic Materials Development for Maritime Applications

Advanced Science
Underwater superhydrophobic surfaces stand as a promising frontier in materials science, holding immense potential for applications in underwater infrastructure, vehicles, pipelines, robots, and sensors.
Zhao Qing Tang, Tongfei Tian, Paul J. Molino, Alex Skvortsov, Dong Ruan, Jie Ding, Yali Li   +6 more
doaj   +1 more source

Civic Crowdfunding as Urban Digital Platform in Milan and Amsterdam: Don’t take pictures on a rainy day!

Digital Geography and Society, 2022
Cities are a conducive context for the emergence of digital platforms and at the same time cities are reshaped by the digital spaces that are created by these platforms.
Letizia Chiappini, Jochem de Vries
doaj   +1 more source

The Digital Architectures of Social Media: Comparing Political Campaigning on Facebook, Twitter, Instagram, and Snapchat in the 2016 U.S. Election

, 2018
The present study argues that political communication on social media is mediated by a platform's digital architecture, defined as the technical protocols that enable, constrain, and shape user behavior in a virtual space.
Bossetta, Michael
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source