Results 51 to 60 of about 967,988 (287)

Recent Advances in Superhydrophobic Materials Development for Maritime Applications

open access: yesAdvanced Science
Underwater superhydrophobic surfaces stand as a promising frontier in materials science, holding immense potential for applications in underwater infrastructure, vehicles, pipelines, robots, and sensors.
Zhao Qing Tang   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Digital Manufacturing Platforms in the Industry 4.0 from Private and Public Perspectives

open access: yesApplied Sciences, 2019
The fourth industrial revolution is characterized by the introduction of the Internet of things (IoT) and Internet of Services (IoS) concepts into manufacturing, which enables smart factories with vertically and horizontally integrated production systems.
Jon Kepa Gerrikagoitia   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Civic Crowdfunding as Urban Digital Platform in Milan and Amsterdam: Don’t take pictures on a rainy day!

open access: yesDigital Geography and Society, 2022
Cities are a conducive context for the emergence of digital platforms and at the same time cities are reshaped by the digital spaces that are created by these platforms.
Letizia Chiappini, Jochem de Vries
doaj   +1 more source

The need for a new legal framework for VTC licenses to allow competition in the services of city transport -including taxis-. A matter of EC Competition Policy [PDF]

open access: yes, 2017
In the recent years, the phenomenon of the sharing economy has played an important part in the market of the city transport of passengers. The performance of these digital platforms such as Uber, Blablacar or Cabify has been full of controversy.
Olmedo-Peralta, Eugenio
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Integration of LIDAR and IFSAR for mapping [PDF]

open access: yes, 2004
LiDAR and IfSAR data is now widely used for a number of applications, particularly those needing a digital elevation model. The data is often complementary to other data such as aerial imagery and high resolution satellite data.
Dowman, I.J.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy