Results 51 to 60 of about 950,229 (283)

Just ticking the box: A social informatics model of the consequences of consent [PDF]

open access: yes, 2019
Given the societal diffusion, proliferation and ubiquity of computerised systems and platforms, it is generally perceived by consumers that systems and eBusiness platforms often pose a threat to the privacy of their supplied information (Srnicek, 2017 ...
Jamieson, David   +2 more
core   +2 more sources

Monitoring post-fire forest recovery using multi-temporal Digital Surface Models generated from different platforms [PDF]

open access: yes, 2016
Wildfires can greatly affect forest dynamics. Given the alteration of fire regimes foreseen globally due to climate and land use changes, greater attention should be devoted to prevention and restoration activities.
Aicardi, Irene   +5 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The need for a new legal framework for VTC licenses to allow competition in the services of city transport -including taxis-. A matter of EC Competition Policy [PDF]

open access: yes, 2017
In the recent years, the phenomenon of the sharing economy has played an important part in the market of the city transport of passengers. The performance of these digital platforms such as Uber, Blablacar or Cabify has been full of controversy.
Olmedo-Peralta, Eugenio
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Dynamics of Transformation in the Development of Digital Services [PDF]

open access: yes, 2018
Service providers are increasingly depending and using digital infrastructure and tools provided by digital platforms to transform their services and develop digital ones that meet the needs of heterogeneous end users. However, while there is an emerging
Ghazawneh, Ahmad
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Towards a Framework of Digital Platform Disruption: A Comparative Study of Centralized & Decentralized Digital Payment Providers [PDF]

open access: yes, 2014
Digital platforms are disruptive information technology (IT) artifacts that erode conventional business logic associated with traditional market structures.
Kazan, Erol   +2 more
core  

Smart Embedded Passive Acoustic Devices for Real-Time Hydroacoustic Surveys [PDF]

open access: yes, 2018
This paper describes cost-efficient, innovative and interoperable ocean passive acoustics sensors systems, developed within the European FP7 project NeXOS (Next generation Low-Cost Multifunctional Web Enabled Ocean Sensor Systems Empowering Marine ...
Artero Delgado, Carola   +11 more
core   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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