Results 41 to 50 of about 883,180 (266)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Developing auto-Didactic (Self-Learning) Skills by Using Social Networking [PDF]
The recent research aims at checking the effectiveness of participating in the social networking sites on auto-didactic skills for university students.
Mohamed Turky, Nardeen Soliman
doaj +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
[Purpose/Significance] Investigating the characteristics of AI-generated academic journal content and establishing a multidimensional analytical framework are crucial for identifying improper use of AIGC in manuscripts, addressing challenges in peer ...
An Tong, Xue Dejun, Zhou Zhe, Kong Xiangyu, Geng Chong
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The Oligopoly of Academic Publishers in the Digital Era
The consolidation of the scientific publishing industry has been the topic of much debate within and outside the scientific community, especially in relation to major publishers' high profit margins. However, the share of scientific output published in the journals of these major publishers, as well as its evolution over time and across various ...
Larivière, Vincent +2 more
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Semantic Publication of Agricultural Scientific Literature Using Property Graphs
During the last decades, there have been significant changes in science that have provoked a big increase in the number of articles published every year. This increment implies a new difficulty for scientists, who have to do an extra effort for selecting
Francisco Abad-Navarro +3 more
doaj +1 more source
The Future of Digital Publishing
Peer review has long been held as the gold standard for article evaluation. At its simplest, the goal of peer review is to ensure that a published article in a journal has been appropriately vetted by qualified scholars. Traditional models require that this process is either single- or double-blind; the editor assigns reviewers based on subject ...
Gonder, Justin +2 more
openaire +3 more sources
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source

