Results 61 to 70 of about 883,180 (266)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Developing virtual museums towards the smart museum: a theoretical study
The study focuses on the latest innovations in virtual applications and virtual reality devices for presenting museum information by reviewing the successive technological developments that have influenced virtual museums, leading to the smart museum ...
Marwa Abdelmajid
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Creative Users, Social Networking, and New Models of Publishing
This paper reviews the changing landscape of the publishing industry, which is being reshaped by dynamics of user co-creation, social networking and open licencing.
Ren Xiang
doaj +1 more source
Osmanlı'dan Günümüze Türkiye'de Yerel Basının Gelişim Süreci
Osmanlı Devleti’nden bugüne Türk basınının yaygın ve yerel ölçekte değişen iletişim yöntemleri, ekonomik, siyasi ve toplumsal koşullara bağlı olarak çeşitli dönüşümler yaşamıştır.
Abdi Erkal, Olcay Uçak
doaj +1 more source
Publishing in the Age of the Digital Doctor
We are living in the middle of a revolution. By the end of this Century of Biology, the fields of medicine and communications will seem utterly unfamiliar to us and would probably seem surreal to our forebears. [...]
openaire +2 more sources
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Türkiye’de Yayıncılık Politikalarının Dönüşümü Üzerine Bir Örnek: E-Yayıncılık
Sözlü kültür sürecinden yazının gelişimine uzanan süreçte destanlarla başlayan bilgi aktarımı, matbaanın icadı ile büyük bir değişim geçirmiştir. 20. ve 21.
Işıl Çobanlı Erdönmez
doaj +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source

