Results 61 to 70 of about 883,180 (266)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Developing virtual museums towards the smart museum: a theoretical study

open access: yesCybrarians Journal
The study focuses on the latest innovations in virtual applications and virtual reality devices for presenting museum information by reviewing the successive technological developments that have influenced virtual museums, leading to the smart museum ...
Marwa Abdelmajid
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Creative Users, Social Networking, and New Models of Publishing

open access: yesCultural Science, 2014
This paper reviews the changing landscape of the publishing industry, which is being reshaped by dynamics of user co-creation, social networking and open licencing.
Ren Xiang
doaj   +1 more source

Osmanlı'dan Günümüze Türkiye'de Yerel Basının Gelişim Süreci

open access: yesSelçuk İletişim, 2019
Osmanlı Devleti’nden bugüne Türk basınının yaygın ve yerel ölçekte değişen iletişim yöntemleri, ekonomik, siyasi ve toplumsal koşullara bağlı olarak çeşitli dönüşümler yaşamıştır.
Abdi Erkal, Olcay Uçak
doaj   +1 more source

Publishing in the Age of the Digital Doctor

open access: yesCurrent Oncology, 2011
We are living in the middle of a revolution. By the end of this Century of Biology, the fields of medicine and communications will seem utterly unfamiliar to us and would probably seem surreal to our forebears. [...]
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Türkiye’de Yayıncılık Politikalarının Dönüşümü Üzerine Bir Örnek: E-Yayıncılık

open access: yesOnline Academic Journal of Information Technology, 2014
Sözlü kültür sürecinden yazının gelişimine uzanan süreçte destanlarla başlayan bilgi aktarımı, matbaanın icadı ile büyük bir değişim geçirmiştir. 20. ve 21.
Işıl Çobanlı Erdönmez
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

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