Results 61 to 70 of about 2,529,720 (311)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Creative Users, Social Networking, and New Models of Publishing

open access: yesCultural Science, 2014
This paper reviews the changing landscape of the publishing industry, which is being reshaped by dynamics of user co-creation, social networking and open licencing.
Ren Xiang
doaj   +1 more source

Several Factors of Library Publishing Services Facilitate Scholarly Communication Functions

open access: yesEvidence Based Library and Information Practice, 2012
Objective – To identify and examine the factors of library publishing services that facilitate scholarly communication. Design – Analysis of library publishing service programs. Setting – North American research libraries. Subjects – Eight
Leslie Bussert
doaj   +1 more source

The future of digital magazine publishing

open access: yesInformation Services and Use, 2011
The publishing industry went through more structural changes in the past ten years than in the whole second half of XX century. In magazine publishing in particular, since the emergence of the first sites to complement the print edition in the 1990s to the release of iPad in 2010, these media have enjoyed numerous opportunities provided by new ...
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Publishing in the Age of the Digital Doctor

open access: yesCurrent Oncology, 2011
We are living in the middle of a revolution. By the end of this Century of Biology, the fields of medicine and communications will seem utterly unfamiliar to us and would probably seem surreal to our forebears. [...]
openaire   +2 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Open Access Publishing: A Literature Review [PDF]

open access: yes, 2014
Within the context of the Centre for Copyright and New Business Models in the Creative Economy (CREATe) research scope, this literature review investigates the current trends, advantages, disadvantages, problems and solutions, opportunities and barriers ...
Frosio, Giancarlo, Derclaye, Estelle
core   +1 more source

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