Results 71 to 80 of about 2,529,720 (311)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Osmanlı'dan Günümüze Türkiye'de Yerel Basının Gelişim Süreci
Selçuk İletişim, 2019 Osmanlı Devleti’nden bugüne Türk basınının yaygın ve yerel ölçekte değişen iletişim yöntemleri, ekonomik, siyasi ve toplumsal koşullara bağlı olarak çeşitli dönüşümler yaşamıştır.
Abdi Erkal, Olcay Uçak
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Scholarly publishing and open access: searching for understanding of an emerging is phenomenon
, 2007 Scholarly publishing is concerned with the distribution of scholarly information through journals and conferences and other information media. As such scholarly publishing can be understood as a specific part of the information industry.
Kautz, Karlheinz +2 more
core +1 more source
Türkiye’de Yayıncılık Politikalarının Dönüşümü Üzerine Bir Örnek: E-Yayıncılık
Online Academic Journal of Information Technology, 2014 Sözlü kültür sürecinden yazının gelişimine uzanan süreçte destanlarla başlayan bilgi aktarımı, matbaanın icadı ile büyük bir değişim geçirmiştir. 20. ve 21.
Işıl Çobanlı Erdönmez
doaj +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Getting to Digital Publishing at WVU [Keynote]
, 2016 Video recording of the keynote session for the 2016 Library Publishing Forum. This presentation discusses digital publishing at West Virginia University and the development of Vega, an open-source academic publishing ...
Ball, Cheryl
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source