Results 21 to 30 of about 82,493 (258)

Transforming the publishing industry in the digital age: challenges and opportunities

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
In the digital age, the publishing industry has been subject to a tremendous revolution brought by technological advancements and changing consumer behavior. This research delves into the disruptions and new opportunities brought on by digitalization to
Alexey Kalmykov
doaj   +1 more source

Digital Scholarly Publishing and Archiving Services by Academic Libraries: Case Study of the University of Patras

Liber Quarterly: The Journal of European Research Libraries, 2010
During the last years, dramatic changes in the electronic publishing landscape have created new roles and changed the traditional ones. Presently, some libraries have capitalised on their experience and knowledge in information technology and electronic ...
Panos Georgiou, Giannis Tsakonas
doaj   +1 more source

Academic Publishing and its Digital Binds: Beyond the Paywall towards Ethical Executions of Code

Culture Unbound: Journal of Current Cultural Research, 2018
In this article we explore various constraints and potentials of academic publishing in the digital age. Advancement of digital platforms and their expansive reach amplify the underlying tensions of institutional and scholarly change. A key affordance of
Teresa Swist, Liam Magee
doaj   +1 more source

Sale of e-books and audiobooks in Ukraine

Інтегровані комунікації, 2023
The research examines the functioning of e-book and audiobook aggregators in Ukraine’s modern publishing market. The development of e-books is crucial for the industry in conditions where the publication of printed material is significantly complicated ...
Viktor Sytnyk
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

The digital transformation of the information professions: Exploring the impact of digital publishing and open access

Information Research: An International Electronic Journal
Introduction. The information professions encompass a range of interconnected disciplines that contribute to the effective creation, processing, management, dissemination, and preservation of information and knowledge in diverse formats and contexts ...
Suliman Hawamdeh, Daniel Alemeneh, Jeff Allen   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Innovations in publishing technologies: Enhancing reader experience

Zeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
In this research, the effects that digitalization has had on existing publishing workflows in the context of content creation, circulation and monetization are explored.
Alexey Kalmykov
doaj   +1 more source