Results 61 to 70 of about 35,630,483 (302)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Design of multi-channel test system based on JTAG interface

Dianzi Jishu Yingyong
The system is designed to realize the automatic acquisition and analysis of radar digital receivers. The digital IQ data is collected and stored by using the JTAG interface of the circuit and the SignalTap function of Quartus software.
Yang Jingsheng
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Investigation of Offset Recovery Algorithms for High-Performance Bluetooth Receivers

, 2005
Research has shown that significant degradation in performance can occur even when operating within the limits for carrier frequency and modulation index offsets permitted by the Bluetooth standard.
Tibenderana, C, Weiss, S, Tibenderana, C., Weiss, S.   +3 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Implementation & Performance Investigation of Dicode PPM over Dispersive Optical Channels [PDF]

This work is concerned with the development and investigation of a Dicode PPM (DiPPM) system. A DiPPM coder was developed to code any input PCM signal into DiPPM format. A further investigation took place on the DiPPM spectrum and associated output.
Charitopoulos, Romanos
core   +4 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Analysis of cyclic delay diversity on DVB-H systems over spatially correlated channel [PDF]

, 2007
The objective of this work is to research and analyze the performance of Cyclic Delay Diversity (CDD) with two transmit antenna on DVB-H systems operating in spatially correlated channel. It is shown in this paper that CDD can achieve desirable transmit
Bari, RD, Loo, KK, Cosmas, J, Zhang, Y, Bard, M, Loo, J., Cosmas, J., Di Bari, R., Bard, M., Zhang, Y.   +9 more
core   +1 more source

A Robust Nonlinear Beamforming Assisted Receiver for BPSK Signalling

, 2005
Nonlinear beamforming designed for wireless communications is investigated. We derive the optimal nonlinear beamforming assisted receiver designed for binary phase shift keying (BPSK) signalling.
Wolfgang, A., Hanzo, L., Chen, S.
core   +1 more source