Results 31 to 40 of about 129,368 (260)

Main Challenges for Child Digital Citizenship in a Consumer Culture in Brazil

open access: yesJournalism and Media, 2022
In this article, we reflect on how practices of children’s consumer culture interfere with the exercise of rights by children who are consumers and producers of content on digital platforms.
Renata Tomaz   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Digital rights in the system of civil rights objects

open access: yesЮридический вестник Самарского университета
The scientific community has met the addition of Article 128 of the Civil Code of the Russian Federation, which specifies the type of property rights as «digital rights» as well as the introduction of Article 141.1 «Digital Rights» with interest.
E. G. Balashova
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

The Digital Transformation and the Right to Health of Young Adults in Bangladesh and Colombia: A Community-Engaged Study [PDF]

open access: yesHealth and Human Rights
In her 2023 report to the United Nations Human Rights Council on digital innovation, technology, and the right to health, the Special Rapporteur on the right to health underscored the positive impact of the digital transformation on young people, but ...
Digital Health And Rights Project Consortium
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Digital human rights: Legal debates and emerging foundations under the international bill of human rights

open access: yesSocial Sciences and Humanities Open
In an era of rapid technological change, recognizing digital rights is essential to ensure equitable access to information, freedom of expression, and social justice.
Mohammad Alsharif, Hussein Hnit
doaj   +1 more source

Inheritance of digital assets: Analyzing the concept of digital inheritance on social media platforms

open access: yesNovum Jus, 2022
We are moving toward a technologically driven world where the traditional way of looking at assets merely from a physical perspective is slowing evolving to include digital assets. With our extreme indulgence in internet activities, we end up creating a
Mohammad Owais Farooqui   +2 more
doaj   +1 more source

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