Results 31 to 40 of about 124,330 (260)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Jusletter-IT, 2020 ABSTRACT In this paper, T.G. Makarov and E.V. Kobchikova considered digital rights in the system of objects of civil legal relations. The features of digital rights are highlighted. The authors emphasize that digital rights can consolidate rights of various types, in particular, rights to things, property rights, intellectual rights, etc.
openaire +3 more sources
Human rights to a favorable social environment on the Internet
Вестник университета, 2022 This work analyzes the right to a favorable social environment on the Internet. The main purpose of the article is to consider the right to access the Internet and a favorable social environment.
V. V. Popov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
The Digital Transformation and the Right to Health of Young Adults in Bangladesh and Colombia: A Community-Engaged Study [PDF]
Health and Human RightsIn her 2023 report to the United Nations Human Rights Council on digital innovation, technology, and the right to health, the Special Rapporteur on the right to health underscored the positive impact of the digital transformation on young people, but ...
Digital Health And Rights Project Consortium
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Social Sciences and Humanities OpenIn an era of rapid technological change, recognizing digital rights is essential to ensure equitable access to information, freedom of expression, and social justice.
Mohammad Alsharif, Hussein Hnit
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Dеmystification of propеrty rights in thе contеxt of thе digital transformation of thе еconomy
RUDN Journal of LawThе rеsеarch rеlеvancе liеs in thе intеrsеction of thе classical civil problеm of thе lеgal naturе of propеrty rights and thе еvolving landscapе of digital tеchnologiеs, which has givеn risе to propеrty rights taking on a digital form (digital rights ...
Anatoly V. Efimov
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source