Results 121 to 130 of about 3,905,794 (341)

Gait Analysis of Pak Biawak: A Necrobot Lizard Built using the Skeleton of an Asian Water Monitor (Varanus Salvator)

open access: yesAdvanced Robotics Research, EarlyView.
Pak Biawak, a necrobot, embodies an unusual fusion of biology and robotics. Designed to repurpose natural structures after death, it challenges conventional boundaries between nature and engineering. Its movements are precise yet unsettling, raising questions about sustainability, ethics, and the untapped potential of biointegrated machines.
Leo Foulds   +2 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

open access: yesAdvanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian   +5 more
wiley   +1 more source

Critical Resolution and Sample Size of Digital Rock Analysis for Unconventional Reservoirs

open access: yesEnergies, 2018
Digital rock analysis (DRA) has exhibited strong ability and significant potential to help people to image geological microstructures and understand transport mechanisms in rocks underground, especially for unconventional reservoirs like tight sandstone ...
Tong Liu, Xu Jin, Moran Wang
doaj   +1 more source

High accuracy capillary network representation in digital rock reveals permeability scaling functions. [PDF]

open access: yesSci Rep, 2021
Neumann RF   +6 more
europepmc   +1 more source

Eelgrass Distribution in the Great Bay Estuary and Piscataqua River for 2017 [PDF]

open access: yes, 2018
Eelgrass distribution in Great Bay, Little Bay, and the Piscataqua River Estuary was mapped from aerial photography acquired on August 24, 2017. The total area of eelgrass beds with 10% or greater cover and a polygon area equal to or greater than 100 ...
Barker, Seth
core   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao   +14 more
wiley   +1 more source

Advancements in digital drilling technology for deep engineering: a review

open access: yesFrontiers in Earth Science
In deep engineering, the in-situ measurement of engineering rock properties is a key issue in projects such as energy storage and resource mining. Numerous researches devoted to adopting the digital drilling methods for the in-situ application of deep ...
Keqi Fan
doaj   +1 more source

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

open access: yesAdvanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying   +8 more
wiley   +1 more source

Stepwise Regulation of Cellular Oxidative Stress via Conductive‐Piezoelectric Integrated Microstructured Conduits for Enhanced Nerve Regeneration

open access: yesAdvanced Science, EarlyView.
This study presents a conductive‐piezoelectric integrated microstructured conduit for peripheral nerve regeneration. The conduit combines reduced graphene oxide with a piezoelectric nanofiber membrane, enhancing nerve repair through physical guidance, oxidative stress inhibition, and ultrasound‐activated electrical stimulation.
Dong Zhou   +9 more
wiley   +1 more source

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