Results 61 to 70 of about 50,915,360 (280)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The role of a digital librarian in the management of digital information systems (DIS) [PDF]
, 2000 Stresses that the multimedia nature of the next generation of digital libraries requires the digital librarians (DL) to be essentially a type of specialist librarian who has to manage and organize the digital library, handle the specialized tasks of ...
Sreenivasulu, V., Sreenivasulu, V
core +1 more source
Digital Library Access For Illiterate Users [PDF]
, 2004 The problems that illiteracy poses in accessing information are gaining attention from the research community. Issues currently being explored include developing an understanding of the barriers to information acquisition experienced by different groups ...
D. M. Nichols +9 more
core
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Molecular Oncology, EarlyView.Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Frontiers in Marine ScienceImplementing Part II of the Biodiversity Beyond National Jurisdiction (BBNJ) Agreement is an opportunity to transform the global approach to access and benefit sharing (ABS) of biological resources, digital sequence information and traditional knowledge.
Fran Humphries, Fran Humphries
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
Browsing a digital library: A new approach for the New Zealand digital library [PDF]
, 2003 Browsing is part of the information seeking process, used when information needs are ill-defined or unspecific. Browsing and searching are often interleaved during information seeking to accommodate changing awareness of information needs.
Sally Jo Cunningham +3 more
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Blue genes, green promises: linking marine gene patents to biotechnology and sustainable development
Frontiers in Marine ScienceMarine genetics play an essential role in biodiversity studies, ecosystem monitoring, and biotechnology, yet little is known about how marine genetic sequences are translated into commercial applications.
Erik Zhivkoplias +6 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source