Results 41 to 50 of about 297,567 (266)

An Event Recognition Method for Φ-OTDR Sensing System Based on Deep Learning

open access: yesSensors, 2019
Phase-sensitive optical time domain reflectometer (Φ-OTDR) based distributed optical fiber sensing system has been widely used in many fields such as long range pipeline pre-warning, perimeter security and structure health monitoring.
Yi Shi, Yuanye Wang, Lei Zhao, Zhun Fan
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Impact of Phase Noise on Range Estimation Accuracy in Harmonic FMCW Radar Systems

open access: yesIEEE Access
This paper investigates the impact of phase noise on range estimation accuracy in harmonic Frequency-Modulated Continuous-Wave (FMCW) radar systems.
Ahmed El-Awamry   +3 more
doaj   +1 more source

Twofold dynamic attention guided deep network and noise-aware mechanism for image denoising

open access: yesJournal of King Saud University: Computer and Information Sciences, 2023
Convolutional neural networks are given extensive attention towards noise removal due to their good performance over traditional denoising algorithms. With shallow conventional neural networks, the feature extraction ability is not profound.
Zihao Chen   +5 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

3D Self-Localization and Tracking with Minimum Anchor Dependency: A Hybrid Measurement and EKF-Based Approach

open access: yesSensors
This paper investigates the feasibility of 3D self-localization and tracking using chipless radio frequency identification (RFID) tags operating in the terahertz (THz) frequency band.
Amani Atiani   +2 more
doaj   +1 more source

A New Method for Building Low-Density-Parity-Check Codes

open access: yesInternational Journal of Technology, 2019
This paper proposes a new method for building low-density-parity-check codes, exempt of cycle of length 4, based on a circulant permutation matrix, which needs very little memory for storage it in the encoder and a dual diagonal structure is applied ...
Tehami Mohammed Amine, Djebbari Ali
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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