Results 51 to 60 of about 2,125,373 (284)

Processing Chain for Localization of Magnetoelectric Sensors in Real Time

Sensors, 2021
The knowledge of the exact position and orientation of a sensor with respect to a source (distribution) is essential for the correct solution of inverse problems.
Christin Bald, Gerhard Schmidt
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Twofold dynamic attention guided deep network and noise-aware mechanism for image denoising

Journal of King Saud University: Computer and Information Sciences, 2023
Convolutional neural networks are given extensive attention towards noise removal due to their good performance over traditional denoising algorithms. With shallow conventional neural networks, the feature extraction ability is not profound.
Zihao Chen, Alex Noel Joseph Raj, Vijayarajan Rajangam, Wei Li, Vijayalakshmi G.V. Mahesh, Zhemin Zhuang   +5 more
doaj   +1 more source

Current state of digital signal processing in myoelectric interfaces and related applications

Biomedical Signal Processing and Control, 2015
This review discusses the critical issues and recommended practices from the perspective of myoelectric interfaces. The major benefits and challenges of myoelectric interfaces are evaluated.
M. Hakonen, H. Piitulainen, A. Visala
semanticscholar   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Impact of Phase Noise on Range Estimation Accuracy in Harmonic FMCW Radar Systems

IEEE Access
This paper investigates the impact of phase noise on range estimation accuracy in harmonic Frequency-Modulated Continuous-Wave (FMCW) radar systems.
Ahmed El-Awamry, Feng Zheng, Thomas Kaiser, Maher Khaliel   +3 more
doaj   +1 more source

A New Method for Building Low-Density-Parity-Check Codes

International Journal of Technology, 2019
This paper proposes a new method for building low-density-parity-check codes, exempt of cycle of length 4, based on a circulant permutation matrix, which needs very little memory for storage it in the encoder and a dual diagonal structure is applied ...
Tehami Mohammed Amine, Djebbari Ali
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source