Results 41 to 50 of about 609,879 (270)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

A Ring-LWE-based digital signature inspired by Lindner–Peikert scheme

Journal of Mathematical Cryptology, 2022
In this article, we give a digital signature by using Lindner–Peikert cryptosystem. The security of this digital signature is based on the assumptions about hardness of Ring-LWE and Ring-SIS problems, along with providing public key and signature of ...
Sharafi Javad, Daghigh Hassan
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Advances in Digital Signature Algorithms: Performance, Security and Future Prospects [PDF]

ITM Web of Conferences
With the rise of online transactions and digital communications, digital signatures have become essential for verifying document integrity and authenticity across fields like finance, government, and healthcare.
Lyu Shuhan
doaj   +1 more source

A Study on the Interoperability Technology of Digital Identification Based on WACI Protocol with Multiparty Distributed Signature

Sensors, 2023
In digital identity authentication, credentials are typically stored in a digital wallet and authenticated through a single key-based signature and public key verification.
Jihwan Kim, Pyung Kim, Daeseon Choi, Younho Lee   +3 more
doaj   +1 more source

Digital Signature Security in Data Communication

, 2018
Authenticity of access in very information are very important in the current era of Internet-based technology, there are many ways to secure information from irresponsible parties with various security attacks, some of technique can use for defend attack
Abdillah, Leon Andretti, Abdullah, Dahlan, Ahmar, Ansari Saleh, Hadi, Ronal, Napitupulu, Darmawan, Nurdiyanto, Heri, Pranolo, Andri, Rahim, Robbi, Rasyidah   +8 more
core   +1 more source

Experimental measurement-device-independent quantum digital signatures over a metropolitan network [PDF]

, 2017
Quantum digital signatures (QDS) provide a means for signing electronic communications with informationtheoretic security. However, all previous demonstrations of quantum digital signatures assume trusted measurement devices. This renders them vulnerable
Andersson, Erika, Chen, Teng-Yun, Curty, Marcos, Jiang, Xiao, Li, Hao, Liu, Hui, Liu, Yang, Ma, Xiongfeng, Pan, Jian-Wei, Puthoor, Ittoop Vergheese, Sun, Xiang-Xiang, Tang, Yan-Lin, Wang, Wei-Long, Wang, Zhen, Yin, Hua-Lei, You, Li-Xing, Zhang, Qiang, Zhang, Wei-Jun, Zhao, Qi   +18 more
core   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

ANALYSIS OF DIGITAL SIGNATURE RULE IN THE ELECTRONIC COMMERCE LAW OF INDONESIA

Mimbar Hukum, 2015
The Indonesian legislature has enacted the Information and Electronic Transaction Bill (the Bill) in 2003, in which digital signature as a technology specific electronic (e) commerce has been promoted.
Irna Nurhayati
doaj  

Data integrity and security of digital signatures on electronic systems using the digital signature algorithm (DSA)

International Journal of Electronics and Communications System, 2021
The digital signature generation process begins with the creation of a public key and a private key. A public key is generated and published to verify the signature and calculate the hash value of the received document.
Asep Saepulrohman, Agus Ismangil
doaj   +1 more source