Results 41 to 50 of about 35,619,964 (296)

A Certified Digital Signature [PDF]

, 2007
A practical digital signature system based on a conventional encryption function which is as secure as the conventional encryption function is described. Since certified conventional systems are available it can be implemented quickly, without the several years delay required for certification of an untested system.
openaire   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Design and implementation of proxy-protected proxy signature based on SM2

网络与信息安全学报, 2017
Based on the SM2 digital signature standard,a proxy-protected proxy signature scheme was designed.Through the design of the agent authorization mechanism,the protection of the proxy signer was realized.The proxy signature was realized by the proxy signer
Qing-xiao GUO, Da-wei ZHANG, Liang CHANG, Xiao-dong LIU, Jing-wen SONG   +4 more
doaj   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A Study on the Interoperability Technology of Digital Identification Based on WACI Protocol with Multiparty Distributed Signature

Sensors, 2023
In digital identity authentication, credentials are typically stored in a digital wallet and authenticated through a single key-based signature and public key verification.
Jihwan Kim, Pyung Kim, Daeseon Choi, Younho Lee   +3 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

XML Security in XML Data Integrity, Authentication, and Confidentiality [PDF]

The widely application of XML has increasingly required high security. XML security confronts some challenges that are strong relating to its features.
Liu, Baolong
core   +4 more sources

ANALYSIS OF DIGITAL SIGNATURE RULE IN THE ELECTRONIC COMMERCE LAW OF INDONESIA

Mimbar Hukum, 2015
The Indonesian legislature has enacted the Information and Electronic Transaction Bill (the Bill) in 2003, in which digital signature as a technology specific electronic (e) commerce has been promoted.
Irna Nurhayati
doaj  

A Ring-LWE-based digital signature inspired by Lindner–Peikert scheme

Journal of Mathematical Cryptology, 2022
In this article, we give a digital signature by using Lindner–Peikert cryptosystem. The security of this digital signature is based on the assumptions about hardness of Ring-LWE and Ring-SIS problems, along with providing public key and signature of ...
Sharafi Javad, Daghigh Hassan
doaj   +1 more source