Results 111 to 120 of about 1,521,825 (346)

E-SKILLS IP – MASTERING THE 21ST CENTURY SKILLS [PDF]

open access: yes, 2015
In this paper we will present the results of a case study carried out with attendees of an Erasmus Intensive Programme (e-skills IP - Competences for Collaboration and Knowledge Sharing in Digital Society), which has promoted the development of 21st ...
Loureiro, Ana
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Enhancing Literacy Instruction through Technology [PDF]

open access: yes, 2018
Technology has altered how children experience language. As technology has taken root in society, literacy skills have expanded beyond simply reading and writing print texts to include interacting with digital texts and media.
Haugen, Kaylin M
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Teacher perceptions of digital life skills in upper secondary school

open access: yesNordic Journal of Comparative and International Education
The introduction of a new curricular reform in 2020 led to life skills becoming a widely discussed topic in Norway. Other commonly debated topics are young people’s technology use and time spent online.
Anja Ramfjord Isaksen   +1 more
doaj   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Impact of Digital Technology on Library Resource Sharing: Revisiting LABELNET in the Digital Age [PDF]

open access: yes, 2006
The digital environment has facilitated resource sharing by breaking the time and distance barriers to efficient document delivery. However, for the librarians, this phenomenon has brought more challenging technical and technological issues demanding ...
Jaswal, Bushra Almas
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Longitudinal Perspective on Digital Skills for Everyday Life: Measurement and Empirical Evidence

open access: yesMedia and Communication
Our everyday lives are increasingly digital: We meet with friends, search for information, watch films, and buy goods online. This generates data that is automatically collected and analyzed.
Kiran Kappeler
doaj   +1 more source

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