Results 71 to 80 of about 2,951,430 (303)

Digital Preservation, Archival Science and Methodological Foundations for Digital Libraries [PDF]

, 2007
Digital libraries, whether commercial, public or personal, lie at the heart of the information society. Yet, research into their long‐term viability and the meaningful accessibility of their contents remains in its infancy. In general, as we have pointed
Ross, Seamus
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

URS: An Unsupervised Radargram Segmentation Network Based on Self-Supervised ViT With Contrastive Feature Learning Framework

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Radar sounders are air and space-borne nadir-looking sensors operating in high-frequency (HF) or very high-frequency (VHF) bands and collect subsurface backscattered returns by transmitting electromagnetic pulses.
Raktim Ghosh, Francesca Bovolo
doaj   +1 more source

Britain needs a digital inclusion policy with concrete targets for both availability and take-up to counter the emergence of a digital underclass [PDF]

, 2011
Internet use and information technology seems ubiquitous throughout our society – for many, life would be unimaginable without it. But, as Ellen Helsper argues, there is a vast ‘digital underclass’ in the UK that has not benefitted from increasing rates ...
Helsper, Ellen
core  

Open budget data: mapping the landscape [PDF]

, 2015
This report offers analysis of the emerging issue of open budget data, which has begun to gain traction amongst advocates and practitioners of financial transparency.
Jonathan Gray
core   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

The Almirall Project: a portal of 19 th century culture and thinking [PDF]

, 2011
The Ateneu Barcelonès is a civil, private cultural association that has been a part of Spanish society and culture since 1860, having been founded with the aim of promoting dialogue and disseminating knowledge about the country's artistic, historical and
Alcaraz-Martínez, Rubén, Burguillos-Martínez, Ferran, Casas-Rivas, Pablo, Montes, Sergi, Vicente-Hernández, Lluís   +4 more
core  

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Auditing the 2020 ‘Christmas Decree’: communicating pandemic restrictions during Italy’s first ‘Covid-Christmas’

Italian Political Science
This article investigates the online public reception of travel restrictions during the Covid-19 pandemic in Italy and the role of civil society in communicating them.
Riccardo Nanni, Maurizio Napolitano
doaj   +2 more sources