Results 131 to 140 of about 32,980 (263)

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

Animal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang, Keru Li, Lei Tan, Wei Chen, Shan Gao, Chenyang Liu, Shuo Pan, Jiayue He, Ning Liu, Gefan Wan, Wei Dong, Weining Kong, Bin Shen, Xiaolong Qi, Yuanwu Ma   +14 more
wiley   +1 more source

Sex Differences in the Association of Simultaneous Decline in Blood Pressure and Decline in Cognition during Aging

Annals of Neurology, EarlyView.
Objective Both high and declining blood pressure (BP) are associated with risk of cognitive decline in older adults, and women have higher rates of hypertension and faster cognitive decline in late‐life. In old age, the relationship between changes in BP and changes in cognition is complex, and although sex differences in cognitive function and decline
Nicholas W. Baumgartner, Ana W. Capuano, Lisa L. Barnes, David A. Bennett, Zoe Arvanitakis   +4 more
wiley   +1 more source

Manga reading on paper vs. digital devices: Prospective effects on core and supportive integration processes in the brain. [PDF]

PLoS One
Umejima K, Sunada Y, Sakai KL.
europepmc   +1 more source

Functional morphology of the pharyngeal teeth of the ocean sunfish, Mola mola

The Anatomical Record, EarlyView.
Abstract Many fish use a set of pharyngeal jaws in their throat to aid in prey capture and processing, particularly of large or complex prey. In this study—combining dissection, CT scanning, histology, and performance testing—we demonstrate a novel use of pharyngeal teeth in the ocean sunfish (Mola mola), a species for which pharyngeal jaw anatomy had ...
Benjamin Flaum, Michael J. Blumer, Mason N. Dean, Laura J. Ekstrom   +3 more
wiley   +1 more source

Remote digital intervention targeting heart failure medical therapy: a randomized controlled trial. [PDF]

Lancet Reg Health Am
DeVore AD, Green CL, Albert NM, Haghighat AR, Chaudhry SP, Shah H, Bennett MK, Stanis T, Govil A, Martyn T, McDermott J, Khan MS, Sauer AJ.   +12 more
europepmc   +1 more source

Genetic diversity and evolutionary services for Nature‐based Solutions

American Journal of Botany, EarlyView.
Alicia Mastretta‐Yanes
wiley   +1 more source

Leveraging Big Multitemporal Multisource Satellite Data and Artificial Intelligence for the Detection of Complex and Invisible Features: The Case of Extensive Irrigation Mapping

Archaeological Prospection, EarlyView.
ABSTRACT The detection of buried or obscured archaeological features remains a central challenge in landscape archaeology, particularly in the irrigated floodplains of Mesopotamia where levees and canals formed the basis of complex agrarian systems. This study presents a deep learning–based approach for the large‐scale, automated detection of ancient ...
Nazarij Buławka, Hector A. Orengo, Felipe Lumbreras Ruiz, Iban Berganzo‐Besga, Ekta Gupta   +4 more
wiley   +1 more source

A method description for developing critical reading skills through a digital platform based on Barrett's taxonomy. [PDF]

MethodsX
Turakulova B, Samatova B, Raxmonova M, Rahmonova D, Ganiyeva G, Jumamurodova U, Norkuziyeva D.   +6 more
europepmc   +1 more source

Legal and ethical considerations around the use of existing illustrations to generate new illustrations in the anatomical sciences

Anatomical Sciences Education, Volume 18, Issue 3, Page 289-300, March 2025.
Abstract It is likely existing anatomical illustrations are often used as the basis for new illustrative works, given not all illustrators have access to human tissues, bodies, or prosections on which to base their illustrations. Potential issues arise with this practice in the realms of copyright infringement and plagiarism when authors are seeking to
Jon Cornwall, Richard White, Patrick Pennefather, Sabine Hildebrandt, Jill Gregory, Heather F. Smith, Jason Organ, Claudia Krebs   +7 more
wiley   +1 more source

Distant Presence: Care Workers' Experiences of Digital Monitoring Systems in Dementia Care. [PDF]

Scand J Caring Sci
Iversen C, Redmalm D, Persson M, Thunman E.   +3 more
europepmc   +1 more source