Results 41 to 50 of about 124,483 (300)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
SAGE OpenAs a major emerging economy, China government debt burden on local governments remains substantial, so enhance fiscal self-sufficiency and debt sustainability is so important.
Wenjun Mai +3 more
doaj +1 more source
, 2017 Shannon's sampling theorem provides a link between the continuous and the discrete realms stating that bandlimited signals are uniquely determined by its values on a discrete set.
Bhandari, Ayush +2 more
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Humanités NumériquesFaced with figures showing a sharp increase in the environmental impact of digital practices, a very recent awareness seems to be emerging among archaeology professionals.
Christophe Tufféry
doaj +1 more source
The psychological mechanism of internet information processing for post-treatment evaluation
Heliyon, 2022 Digital healthcare has been greatly benefiting the public health system, especially during the COVID-19 pandemic. In digital healthcare, information communication through the Internet is crucial. The current study explores how patients' accessibility and
Quan-Hoang Vuong +3 more
doaj +1 more source
Data sufficient products: speculative design explorations for sustainable digital futures [PDF]
Proceedings of the 27th International Academic Mindtrek ConferenceInformation technologies promise to make products and services more efficient and sustainable, yet the ICT industry has a substantial ecological footprint that is only expected to grow. This calls for actions beyond improving product efficiency. To this end, we explore whether demand for data can be moderated by encouraging 'sufficient' usage.
Mathijs Bodelier +3 more
openaire +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Interopérabilité des bases de données scientifiques : une sobriété de façade
Humanités NumériquesAny task is more sustainable if it consumes fewer resources, over its entire lifecycle. Some of the challenges of Digital Humanities are tasks related to interoperability between databases, such as documentation, alignment, migration and publication ...
Régis Witz, Guillaume Porte
doaj +1 more source
A Model-Based Approach to Security Analysis for Cyber-Physical Systems
, 2018 Evaluating the security of cyber-physical systems throughout their life cycle is necessary to assure that they can be deployed and operated in safety-critical applications, such as infrastructure, military, and transportation.
Bakirtzis, Georgios +3 more
core +1 more source